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Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses

Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses

Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses is a chewable tablet providing 3-in-1 protection against fleas, ticks, and heartworms. Priced at $260.56, it's ideal for medium to large dogs needing monthly parasite prevention with proven efficacy and ease of use.

$260.56

● In stock

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Price and availability may change. Click to see current details on CanadaPetCare.

Key features

  • 3-in-1 protection against fleas, ticks, and heartworms
  • Fast-acting: kills fleas in 4 hours, ticks in 8 hours
  • Prevents heartworm disease with moxidectin
  • Controls roundworms and hookworms with pyrantel
  • Beef-flavored chew for easy administration
  • Monthly dosing for consistent year-round protection
  • Trusted formulation by Zoetis animal health

Pros

  • +Broad-spectrum parasite protection
  • +Fast flea and tick kill times
  • +Easy-to-give chewable tablet
  • +Veterinarian-recommended brand
  • +Year supply in one pack
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Cons

  • Higher price than basic flea treatments
  • Not for dogs under 8 weeks old
  • Not recommended for dogs with seizure history

About Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses

What is Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses?

Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses is a monthly chewable tablet designed for dogs weighing between 44.1 and 88 pounds. Formulated to deliver comprehensive parasite protection, it targets fleas, ticks, and heartworms—three of the most common and dangerous pests affecting dogs. Manufactured by Zoetis, this FDA-approved medication combines three active ingredients—sarolaner, moxidectin, and pyrantel—to offer broad-spectrum defense in a single, palatable dose. Each pack contains 12 monthly doses, ensuring a full year of continuous protection.

Key features

  • 3-in-1 Protection — Targets fleas, ticks, and heartworms in one monthly chew.
  • Fast-Acting Formula — Begins killing fleas within 4 hours and ticks within 8 hours.
  • Heartworm Prevention — Contains moxidectin to prevent heartworm disease caused by Dirofilaria immitis.
  • Intestinal Parasite Control — Pyrantel helps eliminate roundworms and hookworms.
  • Beef-Flavored Chew — Palatable tablet that most dogs accept easily.
  • Monthly Dosage — Convenient once-a-month administration for consistent protection.
  • Trusted Brand — Developed by Zoetis, a leading animal health company.

Who is Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses for?

This product is designed for dog owners seeking reliable, year-round protection for medium to large breeds weighing 44.1 to 88 lbs. It’s ideal for pets exposed to outdoor environments where fleas, ticks, and heartworm-carrying mosquitoes are prevalent. Veterinarians often recommend it for dogs in regions with high parasite activity or during peak flea and tick seasons. It's not intended for dogs under 8 weeks of age or those with a history of neurologic disorders like seizures.

How does Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses compare?

Compared to standard flea and tick chews that only target external parasites, Simparica Trio offers added value by preventing heartworm and treating intestinal worms. It outperforms single-purpose treatments like topical spot-ons or collars, which may take longer to act or require more frequent application. While some oral alternatives offer similar protection, Simparica Trio is recognized for its rapid kill speed and high palatability. However, it is priced higher than basic flea preventives, reflecting its broader coverage and pharmaceutical quality.

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Best use cases

  • Year-round flea and tick prevention
  • Heartworm protection in high-risk areas
  • Monthly parasite control for large dogs
  • Replacing multiple separate preventives
  • Travel to tick-endemic regions
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Is Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses right for you?

Simparica Trio is best for owners of medium to large dogs (44.1–88 lbs) seeking comprehensive monthly parasite protection. No special skills needed—just administer one chew per month. Ideal for replacing multiple products with a single solution. Alternatives include NexGard Plus or Sentinel, but Simparica Trio offers faster tick kill and broader coverage.

How it compares: Simparica Trio provides broader protection than standard polypropylene rugs or fixed overhead cranes, offering integrated defense against fleas, ticks, heartworms, and intestinal worms—unlike single-target preventives.

Are There Active CanadaPetCare Coupons for This Product?

Coupon Code ⚠️ Unverified
Expires Aug 26
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Labor Day Special Discount Offer for Frontline Plus Free Shipping! Use Coupon: CPC12ON

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Biggest Labor Day Sale Online! Save Extra 15% Plus Free Shipping on All Orders! Use Coupon: CPC12ON

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Coupon Code ⚠️ Unverified
Expires Aug 26
CanadaPetCare

Special Offer for Labor Day, Save Flat 15% on All Orders Plus Free Shipping! Use Coupon: CPC12ON

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Coupon Code ⚠️ Unverified
Expires Aug 26
CanadaPetCare

Flat 15% Off on Labor Day Blow out Sale Plus Free Shipping on All Usa Orders! Use Coupon: CPC12ON

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Frequently Asked Questions

What does Simparica Trio protect against?

Simparica Trio protects dogs from fleas, ticks, heartworms, roundworms, and hookworms. Its triple-action formula delivers comprehensive monthly parasite prevention for dogs weighing 44.1–88 lbs, making it a full-spectrum solution for pet owners in high-risk areas.

Does Simparica Trio require a prescription?

Yes, Simparica Trio requires a veterinarian's prescription. It is a prescription-only medication due to its active ingredients and intended use in preventing serious parasitic diseases. Always consult your vet before starting any new parasite control program.

How quickly does Simparica Trio work?

Simparica Trio starts killing fleas within 4 hours and ticks within 8 hours of administration. It maintains efficacy throughout the month, providing fast and continuous protection against infestations and disease-carrying parasites.

Is Simparica Trio safe for all dogs?

Simparica Trio is safe for dogs 8 weeks and older weighing 44.1–88 lbs. It should not be used in dogs with a history of seizures or neurologic disorders. Always consult your veterinarian to determine if it's appropriate for your pet.

Can I give Simparica Trio with food?

Yes, Simparica Trio can be given with or without food. The beef-flavored chew is designed to be palatable, but offering it with a small meal may help ensure your dog takes it completely and reduces the chance of mild stomach upset.

How much does Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses cost?

Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses is $260.56 at CanadaPetCare. Prices may change — click through to CanadaPetCare for the latest.

Is Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses in stock at CanadaPetCare?

Yes, Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses is currently in stock at CanadaPetCare.

Are there coupon codes for CanadaPetCare?

Yes — Love Those Deals currently tracks 4 active CanadaPetCare coupons. See the coupons section on this page to copy a code before checkout.

Specifications

Product Type
Pet Supplies~~Pet Flea & Tick Control
Category
Animals & Pet Supplies
SKU
2148
Last updated May 1, 2026