Skip to content
Credelio Plus For Extra Large Dog 22-45kg Blue 6 Chews

Credelio Plus For Extra Large Dog 22-45kg Blue 6 Chews

Credelio Plus For Extra Large Dog 22-45kg Blue 6 Chews is a vet-recommended chewable tablet priced at $99.98 that protects large dogs against fleas, ticks, and mites for up to 35 days per dose. Ideal for proactive parasite prevention in dogs weighing 22-45kg.

$99.98

● In stock

Buy at CanadaPetCare →

Price and availability may change. Click to see current details on CanadaPetCare.

Key features

  • Kills fleas within 8 hours of administration
  • Controls multiple tick species including deer ticks
  • Prevents heartworm with monthly use
  • Tasty chewable form for easy dosing
  • Treats sarcoptic mange and ear mites
  • One chew provides 30 days of protection
  • 6-chew pack for half-year supply

Pros

  • +Fast-acting flea and tick elimination
  • +Oral form avoids messy topical application
  • +Broad-spectrum parasite protection
  • +Veterinarian-recommended and FDA-approved
  • +Convenient monthly dosing schedule
!

Cons

  • Requires prescription from a vet
  • Higher cost than OTC flea treatments
  • Not suitable for dogs under 22kg
  • Potential for mild gastrointestinal side effects

About Credelio Plus For Extra Large Dog 22-45kg Blue 6 Chews

What is Credelio Plus For Extra Large Dog 22-45kg Blue 6 Chews?

Credelio Plus For Extra Large Dog 22-45kg Blue 6 Chews is a prescription-strength, chewable parasite control treatment designed specifically for large dogs weighing between 22 and 45 kilograms. Each pack contains six blue chews, providing a full six months of monthly protection. Manufactured by Elanco, this FDA-approved medication combines lotilaner and moxidectin to deliver broad-spectrum defense against fleas, multiple tick species, and heartworm larvae. It also treats and controls sarcoptic mange and ear mites, making it a comprehensive solution for canine parasite management.

Key features

  • Effective flea and tick control — kills fleas within 8 hours and ticks within 48 hours.
  • Heartworm prevention — contains moxidectin to prevent heartworm disease when used monthly.
  • Chewable and palatable — formulated as a tasty chew, making administration easy for pet owners.
  • Monthly dosing — one chew every 30 days provides continuous protection.
  • Targets multiple parasites — controls deer ticks, lone star ticks, American dog ticks, and brown dog ticks.
  • Backed by veterinary science — developed by Elanco, a trusted name in animal health.
  • Convenient 6-month supply — includes six chews for uninterrupted protection.

Who is Credelio Plus For Extra Large Dog 22-45kg Blue 6 Chews for?

This product is ideal for owners of large breed dogs such as Labradors, German Shepherds, or Golden Retrievers who live in areas with high flea and tick exposure. It's especially beneficial for dogs that spend time outdoors, travel frequently, or reside in regions where heartworm is prevalent. Veterinarians often recommend Credelio Plus for dogs needing reliable, monthly parasite protection without topical applications.

How does Credelio Plus For Extra Large Dog 22-45kg Blue 6 Chews compare?

Compared to standard over-the-counter flea collars or topical treatments, Credelio Plus offers systemic, internal protection that doesn’t wash off with bathing or swimming. Unlike some monthly topicals that require skin absorption, this oral chew begins working faster and covers a broader range of parasites, including heartworm. While similar in function to other prescription chews like NexGard Combo, Credelio Plus stands out for its rapid kill speed and dual active ingredients. It’s a premium option compared to basic flea-only medications, offering integrated tick and heartworm control in one monthly dose.

🎯

Best use cases

  • Monthly flea and tick prevention
  • Heartworm protection in endemic areas
  • Treatment of sarcoptic mange
  • Parasite control for outdoor-active dogs
  • Alternative to topical treatments
🛒

Is Credelio Plus For Extra Large Dog 22-45kg Blue 6 Chews right for you?

Credelio Plus is best for owners of large dogs (22-45kg) seeking reliable, vet-grade parasite protection. A prescription is required, so consult your veterinarian first. It's ideal for those avoiding topical solutions. Alternatives include other prescription chews like Simparica TRIO or topical preventives, but Credelio Plus offers a strong balance of speed, coverage, and convenience.

How it compares: Compared to OTC flea collars or basic topicals, Credelio Plus provides faster, systemic protection against fleas, ticks, and heartworm. It outperforms single-parasite treatments and offers broader coverage than many prescription chews, especially in tick and mite control.

Are There Active CanadaPetCare Coupons for This Product?

Coupon Code ⚠️ Unverified
Expires Aug 26
CanadaPetCare

Labor Day Special Discount Offer for Frontline Plus Free Shipping! Use Coupon: CPC12ON

••••••••

We earn a commission if you shop through this link.

Coupon Code ⚠️ Unverified
Expires Aug 26
CanadaPetCare

Biggest Labor Day Sale Online! Save Extra 15% Plus Free Shipping on All Orders! Use Coupon: CPC12ON

••••••••

We earn a commission if you shop through this link.

Coupon Code ⚠️ Unverified
Expires Aug 26
CanadaPetCare

Special Offer for Labor Day, Save Flat 15% on All Orders Plus Free Shipping! Use Coupon: CPC12ON

••••••••

We earn a commission if you shop through this link.

Coupon Code ⚠️ Unverified
Expires Aug 26
CanadaPetCare

Flat 15% Off on Labor Day Blow out Sale Plus Free Shipping on All Usa Orders! Use Coupon: CPC12ON

••••••••

We earn a commission if you shop through this link.

More from CanadaPetCare

?

Frequently Asked Questions

What does Credelio Plus protect against?

Credelio Plus protects large dogs from fleas, multiple tick species, heartworm larvae, sarcoptic mange, and ear mites. Its dual active ingredients provide broad-spectrum parasite control with one monthly chew.

Does Credelio Plus require a prescription?

Yes, Credelio Plus is a prescription medication. You must have a valid vet prescription to purchase it, ensuring your dog is healthy enough for the treatment and correctly dosed.

How quickly does Credelio Plus kill fleas?

Credelio Plus kills fleas within 8 hours of administration and begins killing ticks within 48 hours. Its fast action helps prevent infestations and reduces disease transmission risk.

Is Credelio Plus safe for all dogs?

Credelio Plus is safe for dogs 22-45kg and 8 weeks or older. It should not be used in dogs with a history of seizures or sensitivity to its ingredients. Consult your vet first.

Can I give Credelio Plus with food?

Yes, Credelio Plus can be given with or without food. Administering it with a meal may help reduce the chance of mild stomach upset in sensitive dogs.

How much does Credelio Plus For Extra Large Dog 22-45kg Blue 6 Chews cost?

Credelio Plus For Extra Large Dog 22-45kg Blue 6 Chews is $99.98 at CanadaPetCare. Prices may change — click through to CanadaPetCare for the latest.

Is Credelio Plus For Extra Large Dog 22-45kg Blue 6 Chews in stock at CanadaPetCare?

Yes, Credelio Plus For Extra Large Dog 22-45kg Blue 6 Chews is currently in stock at CanadaPetCare.

Are there coupon codes for CanadaPetCare?

Yes — Love Those Deals currently tracks 4 active CanadaPetCare coupons. See the coupons section on this page to copy a code before checkout.

Specifications

Product Type
Pet Supplies~~Dog Supplies
Category
Animals & Pet Supplies
SKU
2497
Last updated May 1, 2026