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Simparica TRIO Simparica Trio For Dogs 5.6-11 Lbs (Purple) 12 Doses

Simparica TRIO

Simparica Trio For Dogs 5.6-11 Lbs (Purple) 12 Doses

Simparica Trio For Dogs 5.6-11 Lbs (Purple) 12 Doses is a vet-recommended chewable tablet that protects small dogs against fleas, ticks, and mites. Priced at $141.63, it's ideal for pet owners seeking long-term, monthly parasite control with proven efficacy and ease of use.

$141.63

● In stock

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Key features

  • Triple-action formula targets fleas, ticks, and worms
  • Kills fleas within 4 hours of administration
  • Protects against heartworm, roundworm, and hookworm
  • Once-monthly chewable tablet for year-round use
  • Safe for dogs 8 weeks and older
  • Waterproof and fast-acting
  • Vet-approved and FDA-registered

Pros

  • +Comprehensive parasite protection in one dose
  • +Fast flea and tick kill rate
  • +Easy to administer chewable form
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Cons

  • Not for dogs under 5.6 lbs or under 8 weeks
  • May cause gastrointestinal side effects

About Simparica TRIO Simparica Trio For Dogs 5.6-11 Lbs (Purple) 12 Doses

What is Simparica Trio For Dogs 5.6-11 Lbs (Purple) 12 Doses?

Simparica Trio For Dogs 5.6-11 Lbs (Purple) 12 Doses is a monthly chewable tablet designed for small dogs weighing between 5.6 and 11 pounds. Formulated with three active ingredients—sarolaner, moxidectin, and pyrantel—this FDA-approved medication provides broad-spectrum protection against fleas, ticks (including black-legged, American dog, and brown dog ticks), mange mites, and intestinal worms like roundworms and hookworms. Each purple tablet is easy to administer and starts killing fleas within 4 hours, offering full protection for 30 days. Sold in a 12-dose pack, it ensures a full year of consistent parasite prevention.

Key features

  • Broad-Spectrum Protection — Targets fleas, ticks, mites, roundworms, and hookworms in one monthly dose.
  • Fast-Acting Formula — Begins killing fleas within 4 hours and eliminates 100% of fleas within 12 hours in controlled studies.
  • Convenient Chewable — Palatable tablet that most dogs accept easily, no messy topical application.
  • Year-Round Coverage — 12-dose supply provides continuous protection for one full year.
  • Vet-Recommended — Trusted by veterinarians for safe and effective parasite control in small dogs.
  • Waterproof — Remains effective after swimming, bathing, or exposure to rain.
  • Once-Monthly Dosing — Simplifies scheduling and helps maintain consistent protection.

Who is Simparica Trio For Dogs 5.6-11 Lbs (Purple) 12 Doses for?

This product is specifically formulated for small dogs weighing 5.6 to 11 pounds. It’s ideal for pet owners who want a reliable, all-in-one solution to protect their dogs from common external and internal parasites. It’s especially beneficial for dogs that spend time outdoors, travel frequently, or live in regions with high flea and tick prevalence. Not recommended for puppies under 8 weeks of age or dogs with a history of neurological disorders.

How does Simparica Trio For Dogs 5.6-11 Lbs (Purple) 12 Doses compare?

Compared to standard flea and tick chews that only target external parasites, Simparica Trio offers added protection against heartworms, roundworms, and hookworms—making it a more comprehensive alternative to standalone dewormers or topical treatments. It outperforms many monthly topicals in speed of flea kill and eliminates the risk of user exposure from oily residues. While similar in price to other premium parasite preventives, its triple-action formula provides greater value than single-purpose products like standard polypropylene rugs or fixed overhead cranes in terms of health impact.

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Best use cases

  • Monthly flea and tick prevention
  • Year-round heartworm protection
  • Treatment for roundworm and hookworm
  • Dogs with outdoor exposure
  • Travel or boarding preparation
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Is Simparica Trio For Dogs 5.6-11 Lbs (Purple) 12 Doses right for you?

Simparica Trio is best for owners of small dogs (5.6–11 lbs) seeking a vet-grade, all-in-one parasite preventive. No special skills needed—just monthly dosing. Alternatives include topical treatments or separate dewormers, but Simparica Trio consolidates protection into one convenient chew. Always consult your vet before starting new medication, especially if your dog has health issues.

How it compares: Simparica Trio offers broader protection than flea-only chews or topical treatments, combining internal and external parasite control. It's more convenient and faster-acting than many monthly spot-ons and eliminates the need for multiple products.

Are There Active Pet Express Trading Company Coupons for This Product?

15% Off ⚠️ Unverified
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12% Off ⚠️ Unverified
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12% Off ⚠️ Unverified
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Best Deal for Labor Day Sale Plus Extra 12% Off & Free Shipping on All Orders in Us! Use Coupon: CPC12ON

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Frequently Asked Questions

What does Simparica Trio protect against?

Simparica Trio protects dogs against fleas, ticks (including deer ticks), mange mites, heartworms, roundworms, and hookworms. Its triple-action formula provides comprehensive monthly parasite control for small dogs weighing 5.6–11 lbs.

Does Simparica Trio require a prescription?

Yes, Simparica Trio is a prescription-only medication. You’ll need approval from a licensed veterinarian before purchasing, as it must be used safely based on your dog’s weight, age, and health history.

How quickly does Simparica Trio work?

Simparica Trio starts killing fleas within 4 hours and eliminates 100% of fleas within 12 hours in controlled studies. Tick control begins within 24 hours and lasts for a full month.

Is Simparica Trio safe for small dogs?

Yes, it's formulated specifically for small dogs weighing 5.6–11 lbs and is safe for those 8 weeks and older. However, dogs with a history of seizures or neurological conditions should avoid it.

Can I give Simparica Trio with food?

Yes, you can give Simparica Trio with or without food. Administering it with a meal may help reduce the chance of mild gastrointestinal side effects like vomiting or diarrhea.

How much does Simparica Trio For Dogs 5.6-11 Lbs (Purple) 12 Doses cost?

Simparica Trio For Dogs 5.6-11 Lbs (Purple) 12 Doses is $141.63 at Pet Express Trading Company. Prices may change — click through to Pet Express Trading Company for the latest.

Is Simparica Trio For Dogs 5.6-11 Lbs (Purple) 12 Doses in stock at Pet Express Trading Company?

Yes, Simparica Trio For Dogs 5.6-11 Lbs (Purple) 12 Doses is currently in stock at Pet Express Trading Company.

Are there coupon codes for Pet Express Trading Company?

Yes — Love Those Deals currently tracks 4 active Pet Express Trading Company coupons. See the coupons section on this page to copy a code before checkout.

Specifications

Brand
Simparica TRIO
Product Type
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
Category
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
SKU
3915
MPN
Simparica-TRIO-2139
Last updated Apr 28, 2026