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Simparica TRIO Simparica Trio For Dogs 44.1-88 Lbs (Green) 6 Doses

Simparica TRIO

Simparica Trio For Dogs 44.1-88 Lbs (Green) 6 Doses

Simparica Trio For Dogs 44.1-88 Lbs (Green) 6 Doses is a vet-recommended chewable tablet that protects dogs against fleas, ticks, and heartworm. Priced at $118.53, it's ideal for medium to large dogs needing year-round parasite defense with minimal effort from owners.

$118.53

● In stock

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Key features

  • Protects against fleas, ticks, heartworm, roundworms, hookworms
  • Kills fleas within 4 hours, ticks within 8 hours
  • Monthly chewable tablet for 6 months of coverage
  • For dogs 44.1-88 lbs, 8 weeks and older
  • Palatable green chew, easy to administer
  • FDA-approved, vet-recommended by Zoetis
  • No messy topicals or collars needed

Pros

  • +Comprehensive parasite protection in one dose
  • +Fast-acting and long-lasting
  • +Easy to give, most dogs love the taste
  • +Trusted brand with clinical backing
  • +Reduces need for multiple medications
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Cons

  • Higher upfront cost than single-target preventives
  • Requires monthly administration
  • Not suitable for dogs under 44.1 lbs
  • Prescription may be required

About Simparica TRIO Simparica Trio For Dogs 44.1-88 Lbs (Green) 6 Doses

What is Simparica Trio For Dogs 44.1-88 Lbs (Green) 6 Doses?

Simparica Trio For Dogs 44.1-88 Lbs (Green) 6 Doses is a monthly chewable tablet designed for medium to large dogs weighing between 44.1 and 88 pounds. Manufactured by Zoetis, this FDA-approved medication provides broad-spectrum protection against six major parasites: fleas, ticks (including black-legged, American dog, and lone star ticks), heartworm disease, roundworms, and hookworms. Each pack contains six pre-measured green chews, offering half a year of continuous protection. It is administered orally once a month and is recommended for dogs 8 weeks of age and older.

Key features

  • Broad-Spectrum Protection — Targets fleas, ticks, heartworm, roundworms, and hookworms in one monthly dose.
  • Fast-Acting Formula — Starts killing fleas within 4 hours and ticks within 8 hours of administration.
  • Convenient Chewable Form — Palatable green tablet that most dogs accept easily, no pill pockets required.
  • Long-Lasting Monthly Coverage — One dose provides full protection for 30 days.
  • Vet-Recommended Brand — Developed by Zoetis, a trusted name in veterinary medicine.
  • Six-Month Supply — Includes 6 doses for uninterrupted parasite control.
  • Safe for Dogs 8 Weeks+ — Approved for puppies and adult dogs within the specified weight range.

Who is Simparica Trio For Dogs 44.1-88 Lbs (Green) 6 Doses for?

This product is ideal for dog owners seeking a reliable, all-in-one parasite preventive for medium to large breeds such as Labrador Retrievers, German Shepherds, or Bulldogs. It’s especially beneficial for pets that spend time outdoors, travel frequently, or live in regions with high tick or mosquito activity. It's also suitable for households wanting to simplify their pet care routine with a single monthly chew instead of multiple treatments.

How does Simparica Trio For Dogs 44.1-88 Lbs (Green) 6 Doses compare?

Compared to standalone flea or tick preventives, Simparica Trio offers broader protection by also preventing heartworm, roundworm, and hookworm. It outperforms standard polypropylene-based collars and topical treatments in speed and convenience. Unlike some generics, it’s backed by extensive clinical research and veterinary endorsement. While pricier than basic flea chews, its comprehensive coverage reduces the need for multiple products, offering better long-term value.

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Best use cases

  • Year-round flea and tick prevention
  • Heartworm protection in high-risk areas
  • Multi-parasite control for outdoor dogs
  • Simplified medication for busy owners
  • Veterinary-recommended preventive care
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Is Simparica Trio For Dogs 44.1-88 Lbs (Green) 6 Doses right for you?

Simparica Trio is best for owners of medium to large dogs (44.1-88 lbs) seeking a comprehensive, monthly chewable solution for parasite control. No special skills needed—just administer once a month with food. Consider alternatives like generic heartworm preventives or topical flea treatments if cost is a concern, but note they may not offer the same broad coverage.

How it compares: Simparica Trio offers broader protection than single-target flea chews or tick collars. It combines the benefits of heartworm preventives, dewormers, and tick killers in one fast-acting chew, reducing treatment complexity compared to using multiple separate products.

Are There Active Pet Express Trading Company Coupons for This Product?

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12% Off ⚠️ Unverified
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Frequently Asked Questions

What does Simparica Trio protect against?

Simparica Trio protects dogs against fleas, ticks (including deer ticks and lone star ticks), heartworm disease, roundworms, and hookworms. It’s a full-spectrum parasite preventive designed for comprehensive monthly protection in dogs weighing 44.1 to 88 lbs.

Does Simparica Trio require a prescription?

Yes, Simparica Trio typically requires a prescription from a licensed veterinarian. It’s an FDA-approved medication, and your vet must confirm your dog’s weight, age, and health status before use to ensure safety and proper dosing.

How quickly does Simparica Trio work?

Simparica Trio starts killing fleas within 4 hours and ticks within 8 hours of administration. It maintains full protection for 30 days, making it one of the fastest-acting oral parasite preventives available for dogs.

Is Simparica Trio safe for all dogs?

Simparica Trio is safe for dogs 8 weeks and older weighing 44.1 to 88 lbs. It has not been proven safe for breeding, pregnant, or lactating dogs. Always consult your vet before starting any new medication.

Can I split the dose for a smaller dog?

No, Simparica Trio doses should not be split. Each chew is formulated for a specific weight range. Using a split dose may result in under-dosing and reduced effectiveness. Use the appropriately sized chew for your dog’s weight.

How much does Simparica Trio For Dogs 44.1-88 Lbs (Green) 6 Doses cost?

Simparica Trio For Dogs 44.1-88 Lbs (Green) 6 Doses is $118.53 at Pet Express Trading Company. Prices may change — click through to Pet Express Trading Company for the latest.

Is Simparica Trio For Dogs 44.1-88 Lbs (Green) 6 Doses in stock at Pet Express Trading Company?

Yes, Simparica Trio For Dogs 44.1-88 Lbs (Green) 6 Doses is currently in stock at Pet Express Trading Company.

Are there coupon codes for Pet Express Trading Company?

Yes — Love Those Deals currently tracks 4 active Pet Express Trading Company coupons. See the coupons section on this page to copy a code before checkout.

Specifications

Brand
Simparica TRIO
Product Type
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
Category
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
SKU
3915
GTIN
87219131602
MPN
Simparica-TRIO-2147
Last updated Apr 28, 2026