Skip to content
Simparica TRIO Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses

Simparica TRIO

Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses

Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses is a vet-recommended chewable tablet that protects dogs against fleas, ticks, and heartworm. Priced at $61.83, it's ideal for medium to large dogs needing monthly broad-spectrum parasite control.

$61.83

● In stock

Buy at Pet Express Trading Company →

Price and availability may change. Click to see current details on Pet Express Trading Company.

Key features

  • Broad-spectrum protection from fleas, ticks, heartworm
  • Chewable tablet for dogs 44.1–88 lbs
  • Kills fleas within 4 hours of dosing
  • Monthly oral treatment with 3-dose supply
  • Prescription-based for safety and efficacy
  • Fast-acting against multiple parasites
  • Backed by veterinary recommendation

Pros

  • +Kills fleas fast, within 4 hours
  • +Protects against 5 types of parasites
  • +Easy to administer chewable form
  • +Trusted by veterinarians
  • +Convenient 3-month supply
!

Cons

  • Requires prescription
  • Higher cost than basic flea treatments
  • Not for dogs under 44.1 lbs
  • Potential side effects like vomiting

About Simparica TRIO Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses

What is Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses?

Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses is a prescription chewable tablet designed for medium to large dogs. It provides comprehensive protection against fleas, ticks, heartworm, roundworm, and hookworm. Each green chewable dose is formulated for dogs weighing between 44.1 and 88 pounds, offering one month of parasite prevention. Sold in a 3-dose pack, it’s a convenient option for pet owners seeking reliable, monthly protection with minimal effort. Available through Pet Express Trading Company at $61.83, this product is backed by a moneyback guarantee and fast delivery.

Key features

  • Broad-Spectrum Protection — Targets fleas, ticks, heartworm, roundworm, and hookworm in one monthly dose.
  • Easy Administration — Palatable chewable tablet that most dogs accept readily.
  • Weight-Specific Dosing — Green chew formulated for dogs 44.1–88 lbs to ensure accurate dosing.
  • 3-Month Supply — Includes three monthly doses for continuous protection.
  • Vet-Recommended — Trusted by veterinarians for effective parasite control.
  • Fast-Acting — Begins killing fleas within 4 hours and ticks within 8 hours.
  • Prescription-Based — Requires veterinary approval to ensure pet safety and suitability.

Who is Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses for?

This product is ideal for owners of medium to large dogs who live in areas with high flea and tick exposure or require year-round heartworm prevention. It’s especially beneficial for busy pet owners who prefer a simple, once-monthly chewable solution. Dogs with outdoor access, those who hike or travel, or live in regions with mosquito-borne heartworm risk will benefit most. A prescription is required, so it’s best suited for pet owners with access to veterinary care.

How does Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses compare?

Compared to single-action flea or tick preventives, Simparica Trio offers broader protection by also preventing heartworm, roundworm, and hookworm. It outperforms topical treatments by eliminating skin residue concerns and offering faster flea kill times. Unlike some oral preventives that require fasting, this chew can be given with or without food. While more expensive than basic flea collars or generic chews, its comprehensive coverage justifies the $61.83 price for many pet owners. It’s a step above standard polypropylene rugs in parasite control—offering medical-grade defense rather than limited environmental protection.

🎯

Best use cases

  • Monthly flea and tick prevention
  • Heartworm protection in high-risk areas
  • Dogs with outdoor or hiking exposure
  • Year-round parasite control
  • Owners preferring oral medication
🛒

Is Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses right for you?

Simparica Trio is best for owners of medium to large dogs seeking comprehensive, monthly parasite protection. A prescription is required, so consult your vet first. Ideal for pet owners who prefer oral chews over topicals. Alternatives include Bravecto or generic heartworm preventives, but Simparica Trio offers broader coverage. At $61.83, it's a premium option with medical-grade benefits.

How it compares: Simparica Trio offers broader protection than single-target flea chews or topical treatments. It surpasses standard polypropylene rugs and basic collars by providing internal parasite prevention, including heartworm, making it a medical solution versus environmental control.

Are There Active Pet Express Trading Company Coupons for This Product?

15% Off ⚠️ Unverified
Expires Aug 26
Pet Express Trading Company

Flat 15% Off on Labor Day Blow out Sale Plus Free Shipping on All Usa Orders! Use Coupon: CPC12ON

••••••••

We earn a commission if you shop through this link.

12% Off ⚠️ Unverified
Expires Aug 26
Pet Express Trading Company

Enjoy 12% Discount on All Pet Supplies Products for Labor Day Sale Plus Free Shipping! Use Coupon: CPC12ON

••••••••

We earn a commission if you shop through this link.

12% Off ⚠️ Unverified
Expires Aug 26
Pet Express Trading Company

Best Deal for Labor Day Sale Plus Extra 12% Off & Free Shipping on All Orders in Us! Use Coupon: CPC12ON

••••••••

We earn a commission if you shop through this link.

15% Off ⚠️ Unverified
Expires Apr 14
Pet Express Trading Company

Egg-clusive 15% OFF Coupon!

••••••••

We earn a commission if you shop through this link.

More from Pet Express Trading Company

?

Frequently Asked Questions

What does Simparica Trio protect against?

Simparica Trio protects dogs from fleas, ticks, heartworm, roundworm, and hookworm. It’s a broad-spectrum preventive that kills fleas within 4 hours and ticks within 8 hours, offering comprehensive monthly protection for dogs weighing 44.1–88 lbs.

Does Simparica Trio require a prescription?

Yes, Simparica Trio requires a prescription from a licensed veterinarian. This ensures the medication is safe and appropriate for your dog’s health condition and weight, reducing the risk of adverse reactions.

How quickly does Simparica Trio work?

Simparica Trio begins killing fleas within 4 hours and ticks within 8 hours of administration. It maintains full protection for a full month, making it one of the fastest-acting oral parasite preventives available.

Is Simparica Trio safe for all dogs?

Simparica Trio is safe for dogs weighing 44.1–88 lbs and at least 8 weeks old. It’s not recommended for dogs with a history of seizures. Always consult your vet before starting any new medication.

Can I give Simparica Trio with food?

Yes, Simparica Trio can be given with or without food. The chewable tablet is designed to be palatable, making administration easier. Giving it with a meal may help reduce the chance of vomiting.

How much does Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses cost?

Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses is $61.83 at Pet Express Trading Company. Prices may change — click through to Pet Express Trading Company for the latest.

Is Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses in stock at Pet Express Trading Company?

Yes, Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses is currently in stock at Pet Express Trading Company.

Are there coupon codes for Pet Express Trading Company?

Yes — Love Those Deals currently tracks 4 active Pet Express Trading Company coupons. See the coupons section on this page to copy a code before checkout.

Specifications

Brand
Simparica TRIO
Product Type
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
Category
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
SKU
3915
MPN
Simparica-TRIO-2146
Last updated Apr 28, 2026