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Simparica TRIO Simparica Trio For Dogs 22.1-44 Lbs (Blue) 3 Doses

Simparica TRIO

Simparica Trio For Dogs 22.1-44 Lbs (Blue) 3 Doses

Simparica Trio For Dogs 22.1-44 Lbs (Blue) 3 Doses is a vet-recommended chewable tablet that protects dogs against fleas, ticks, and heartworm. Priced at $47.13, it's ideal for medium-sized dogs needing monthly broad-spectrum parasite control.

$47.13

● In stock

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Key features

  • Broad-spectrum protection from fleas, ticks, and worms
  • Kills fleas within 4 hours of dosing
  • Monthly chewable tablet with palatable flavor
  • Protects against heartworm, roundworm, and hookworm
  • 3-dose pack for 3 months of coverage
  • For dogs 22.1–44 lbs (blue color-coded packaging)
  • FDA-approved, vet-recommended formula

Pros

  • +One tablet replaces multiple parasite preventives
  • +Fast flea and tick kill action
  • +Easy to administer with food
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Cons

  • Requires prescription
  • Not for dogs under 8 weeks

About Simparica TRIO Simparica Trio For Dogs 22.1-44 Lbs (Blue) 3 Doses

What is Simparica Trio For Dogs 22.1-44 Lbs (Blue) 3 Doses?

Simparica Trio For Dogs 22.1-44 Lbs (Blue) 3 Doses is a prescription chewable tablet designed for medium-sized dogs weighing between 22.1 and 44 pounds. Formulated to combat multiple parasites, it provides monthly protection against fleas, ticks, heartworm disease, roundworms, and hookworms. Each pack contains three doses, offering three months of continuous defense. Manufactured by Zoetis, Simparica Trio is FDA-approved and commonly recommended by veterinarians for comprehensive internal and external parasite control.

Key features

  • Broad-Spectrum Protection — Targets fleas, ticks, heartworm, roundworm, and hookworm in one monthly dose.
  • Fast-Acting Formula — Starts killing fleas within 4 hours and ticks within 8 hours of administration.
  • Convenient Chewable Tablet — Palatable flavor makes administration easy; no topical application needed.
  • Monthly Dosage Pack — Includes 3 pre-measured tablets for 3 months of protection.
  • For Medium-Sized Dogs — Specifically dosed for dogs weighing 22.1–44 lbs (blue packaging).
  • Prescription-Based — Requires veterinary approval to ensure safe and appropriate use.
  • Trusted Brand — Produced by Zoetis, a leading animal health company with clinical backing.

Who is Simparica Trio For Dogs 22.1-44 Lbs (Blue) 3 Doses for?

This product is ideal for dog owners seeking a reliable, all-in-one parasite preventive for medium-sized breeds. It’s especially beneficial for pets in regions with high tick and mosquito activity, where heartworm and tick-borne diseases are prevalent. Suitable for dogs 8 weeks of age and older, it’s a top choice for pet parents who want a single monthly solution instead of juggling multiple preventives.

How does Simparica Trio For Dogs 22.1-44 Lbs (Blue) 3 Doses compare?

Compared to single-purpose flea or tick treatments, Simparica Trio offers broader protection in one tablet. It outperforms standard polypropylene rugs in parasite control efficacy. Unlike topical solutions, it eliminates skin residue concerns. When stacked against other oral preventives like standard heartworm chews, it adds flea and tick control, reducing the need for additional products. While pricier than basic generics, its comprehensive action justifies the cost for many pet owners.

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Best use cases

  • Monthly flea and tick prevention
  • Heartworm protection in high-risk areas
  • Deworming for roundworm and hookworm
  • All-in-one solution for busy pet owners
  • Veterinary-recommended parasite control
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Is Simparica Trio For Dogs 22.1-44 Lbs (Blue) 3 Doses right for you?

Simparica Trio is best for owners of medium-sized dogs (22.1–44 lbs) seeking a comprehensive, vet-approved parasite preventive. No special skills needed—just administer monthly with food. Requires a prescription, so consult your vet first. Alternatives include separate heartworm and flea-tick products, but Simparica Trio consolidates protection into one chewable.

How it compares: Simparica Trio offers broader protection than single-target flea chews or topical treatments. It combines benefits of heartworm preventives and tick control meds, reducing the need for multiple products. More effective than standard polypropylene rugs in parasite defense.

Are There Active Pet Express Trading Company Coupons for This Product?

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12% Off ⚠️ Unverified
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Frequently Asked Questions

What does Simparica Trio protect against?

Simparica Trio protects dogs from fleas, ticks, heartworm disease, roundworms, and hookworms. It’s a broad-spectrum preventive that combines multiple medications into one monthly chewable tablet, making it ideal for comprehensive parasite control.

Does Simparica Trio require a prescription?

Yes, Simparica Trio requires a prescription from a licensed veterinarian. This ensures the medication is safe for your dog’s health status and weight, and confirms they’ve been tested for heartworm before starting treatment.

How quickly does Simparica Trio kill fleas and ticks?

Simparica Trio starts killing fleas within 4 hours and ticks within 8 hours after administration. It provides continuous protection for a full month, helping prevent infestations and disease transmission.

Is Simparica Trio safe for all dogs?

Simparica Trio is safe for dogs 8 weeks of age and older weighing 22.1–44 lbs. It has not been evaluated for use in breeding, pregnant, or lactating dogs. Always consult your vet before starting any new medication.

Can I buy Simparica Trio without a vet visit?

No, you cannot legally purchase Simparica Trio without a prescription. A vet must first examine your dog and confirm they are heartworm-negative before authorizing the medication for safety reasons.

How much does Simparica Trio For Dogs 22.1-44 Lbs (Blue) 3 Doses cost?

Simparica Trio For Dogs 22.1-44 Lbs (Blue) 3 Doses is $47.13 at Pet Express Trading Company. Prices may change — click through to Pet Express Trading Company for the latest.

Is Simparica Trio For Dogs 22.1-44 Lbs (Blue) 3 Doses in stock at Pet Express Trading Company?

Yes, Simparica Trio For Dogs 22.1-44 Lbs (Blue) 3 Doses is currently in stock at Pet Express Trading Company.

Are there coupon codes for Pet Express Trading Company?

Yes — Love Those Deals currently tracks 4 active Pet Express Trading Company coupons. See the coupons section on this page to copy a code before checkout.

Specifications

Brand
Simparica TRIO
Product Type
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
Category
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
SKU
3915
MPN
Simparica-TRIO-2143
Last updated Apr 28, 2026