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Simparica TRIO Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 12 Doses

Simparica TRIO

Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 12 Doses

Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 12 Doses is a vet-recommended chewable tablet that protects dogs against fleas, ticks, and mites. Priced at $146.88, it offers 12 months of monthly protection for small to medium dogs weighing 11.1–22 lbs.

$146.88

● In stock

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Key features

  • Protects against fleas, ticks, mites, roundworms, and hookworms
  • Caramel-flavored chew for easy administration
  • 12 monthly doses for year-round protection
  • Fast-acting: kills fleas in 4 hours, ticks in 8 hours
  • For dogs 11.1–22 lbs, 8 weeks and older
  • Prescription required for safe use
  • Veterinarian-recommended brand

Pros

  • +Comprehensive parasite protection in one chew
  • +Fast flea and tick kill time
  • +Pleasant caramel flavor dogs like
  • +Convenient monthly dosing
  • +Backed by veterinary trust
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Cons

  • Requires prescription
  • Not for dogs under 8 weeks
  • Higher upfront cost than basic preventives

About Simparica TRIO Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 12 Doses

What is Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 12 Doses?

Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 12 Doses is a monthly chewable tablet designed for dogs in the 11.1 to 22-pound weight range. Formulated with three active ingredients—sarolaner, moxidectin, and pyrantel—this medication provides broad-spectrum protection against fleas, ticks (including black-legged, American dog, and brown dog ticks), mange mites, and intestinal worms like roundworms and hookworms. The caramel-flavored chew is easy to administer and is given once a month for continuous protection. It's a prescription product recommended by veterinarians for comprehensive parasite control in dogs.

Key features

  • Broad-Spectrum Protection — Targets fleas, ticks, mites, roundworms, and hookworms in one monthly dose.
  • Caramel Flavor — Palatable chew that most dogs accept easily, reducing administration stress.
  • Monthly Dosage — 12 pre-measured chews for year-round protection.
  • Prescription-Based — Requires veterinary approval to ensure safe and appropriate use.
  • Fast-Acting — Begins killing fleas within 4 hours and ticks within 8 hours of administration.
  • Weight-Specific Formula — Tailored for dogs weighing 11.1–22 lbs to ensure accurate dosing.
  • Trusted Brand — From the makers of Simparica, a well-known name in veterinary parasite control.

Who is Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 12 Doses for?

This product is ideal for dog owners with small to medium-sized dogs who want a reliable, all-in-one parasite prevention solution. It’s especially beneficial for pets that spend time outdoors, live in tick-prone areas, or require year-round deworming. It is not suitable for dogs under 8 weeks of age or those with a history of neurological disorders. Always consult your vet before starting any new medication.

How does Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 12 Doses compare?

Compared to single-purpose flea or tick preventives, Simparica Trio offers broader protection by also targeting internal parasites like roundworms and hookworms. It outperforms standard polypropylene collars and over-the-counter topical treatments in both speed and spectrum of action. Unlike some monthly chews that only address external parasites, Simparica Trio combines internal and external parasite control in one convenient dose. It is comparable to other prescription combination chews but stands out for its rapid kill time and palatable flavor.

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Best use cases

  • Year-round flea and tick prevention
  • Deworming for roundworms and hookworms
  • Protection for dogs in tick-endemic areas
  • Monthly parasite control for small dogs
  • Veterinary-recommended preventive care
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Is Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 12 Doses right for you?

Simparica Trio is best for dog owners seeking a comprehensive, vet-approved parasite solution for small to medium dogs. It requires a prescription, so consult your veterinarian first. Ideal for those who prefer a chewable over topicals. Alternatives include other prescription chews like NexGard Combo or topical treatments, but Simparica Trio offers broader coverage.

How it compares: Simparica Trio provides broader protection than single-target flea or tick products and outperforms standard collars and OTC topicals. It matches other prescription combination chews but offers faster kill times and better palatability.

Are There Active Pet Express Trading Company Coupons for This Product?

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12% Off ⚠️ Unverified
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Best Deal for Labor Day Sale Plus Extra 12% Off & Free Shipping on All Orders in Us! Use Coupon: CPC12ON

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Frequently Asked Questions

What does Simparica Trio protect against?

Simparica Trio protects dogs from fleas, ticks (including deer ticks), mange mites, roundworms, and hookworms. It’s a three-in-one preventive that covers both external and internal parasites commonly found in dogs, especially those in high-risk environments.

Does Simparica Trio require a prescription?

Yes, Simparica Trio requires a prescription from a licensed veterinarian. This ensures the medication is safe for your dog’s health status and weight, and helps prevent misuse in animals with certain medical conditions or breed sensitivities.

How quickly does Simparica Trio work?

Simparica Trio begins killing fleas within 4 hours and ticks within 8 hours of administration. It maintains effectiveness throughout the month, providing continuous protection against reinfestation and new parasite exposure.

Is Simparica Trio safe for all dogs?

Simparica Trio is safe for dogs 8 weeks and older weighing 11.1–22 lbs. It should not be used in dogs with a history of seizures or neurological disorders. Always consult your vet before starting treatment.

Can I buy Simparica Trio without a vet visit?

No, you cannot legally purchase Simparica Trio without a valid prescription. Most online retailers, including Pet Express Trading Company, require prescription verification before shipping to ensure responsible use and pet safety.

How much does Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 12 Doses cost?

Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 12 Doses is $146.88 at Pet Express Trading Company. Prices may change — click through to Pet Express Trading Company for the latest.

Is Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 12 Doses in stock at Pet Express Trading Company?

Yes, Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 12 Doses is currently in stock at Pet Express Trading Company.

Are there coupon codes for Pet Express Trading Company?

Yes — Love Those Deals currently tracks 4 active Pet Express Trading Company coupons. See the coupons section on this page to copy a code before checkout.

Specifications

Brand
Simparica TRIO
Product Type
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
Category
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
SKU
3915
MPN
Simparica-TRIO-2142
Last updated Apr 28, 2026