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Credelio Plus Credelio Plus For Extra Large Dog 22-45kg Blue 12 Chews

Credelio Plus

Credelio Plus For Extra Large Dog 22-45kg Blue 12 Chews

Credelio Plus For Extra Large Dog 22-45kg Blue 12 Chews is a vet-recommended chewable tablet for dogs 22-45kg, priced at $218.28. It prevents fleas, ticks, and mites for a full month. Ideal for large breed owners seeking reliable, monthly parasite protection with easy administration.

$218.28

● In stock

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Key features

  • Kills fleas and ticks for 30 days
  • Prevents heartworm disease
  • Beef-flavored chew for easy dosing
  • For dogs 22-45kg
  • 12-month supply included
  • Vet-prescribed and trusted brand
  • No food restrictions for administration

Pros

  • +Highly effective against multiple parasites
  • +Easy to administer chewable tablet
  • +Includes heartworm prevention
  • +Trusted by veterinarians
  • +One dose per month
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Cons

  • Requires prescription
  • Higher cost than OTC options
  • Not for dogs under 22kg
  • Potential side effects in sensitive dogs

About Credelio Plus Credelio Plus For Extra Large Dog 22-45kg Blue 12 Chews

What is Credelio Plus For Extra Large Dog 22-45kg Blue 12 Chews?

Credelio Plus For Extra Large Dog 22-45kg Blue 12 Chews is a prescription-strength, chewable parasite control treatment designed specifically for large dogs weighing between 22 and 45 kilograms. Each pack contains 12 monthly doses, providing year-round protection against fleas, ticks, and mites. Manufactured by Elanco, Credelio Plus combines lotilaner and moxidectin to deliver broad-spectrum defense, including heartworm prevention. The chews are beef-flavored, making them palatable and easy to administer without food restrictions.

Key features

  • Flea and Tick Control — Kills fleas and major tick species including black-legged, American dog, and brown dog ticks.
  • Heartworm Prevention — Contains moxidectin to prevent heartworm disease when used monthly.
  • Monthly Protection — One chew every 30 days provides continuous, reliable parasite control.
  • Beef-Flavored Chew — Palatable formula that most dogs accept willingly, no need to hide in food.
  • For Large Dogs — Specifically dosed for dogs 22-45kg, ensuring safety and efficacy.
  • 12-Dose Supply — Full year of protection in one package, reducing refill frequency.
  • Vet-Recommended — Trusted brand used and prescribed by veterinarians nationwide.

Who is Credelio Plus For Extra Large Dog 22-45kg Blue 12 Chews for?

This product is ideal for owners of large breed dogs such as Labradors, German Shepherds, or Golden Retrievers who live in areas with high flea and tick exposure. It’s especially beneficial for pet parents seeking a convenient, once-a-month oral solution that also protects against heartworm. Dogs with sensitive skin or allergies to topical treatments may also benefit from this oral alternative. A prescription is required, so consultation with a veterinarian is necessary before use.

How does Credelio Plus For Extra Large Dog 22-45kg Blue 12 Chews compare?

Compared to standard flea and tick collars or topical treatments, Credelio Plus offers systemic protection without residue or skin contact concerns. Unlike some oral generics, it combines dual active ingredients for broader coverage, including heartworm prevention—something many standalone flea/tick chews lack. It’s more convenient than monthly pipettes and avoids the mess associated with spot-ons. While pricier than basic over-the-counter options, its veterinary-grade formulation and comprehensive protection justify the cost for proactive pet owners.

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Best use cases

  • Monthly flea and tick prevention
  • Heartworm protection in endemic areas
  • Alternative to topical treatments
  • Year-round parasite control
  • For large breed dogs 22-45kg
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Is Credelio Plus For Extra Large Dog 22-45kg Blue 12 Chews right for you?

Credelio Plus is best for owners of large dogs needing comprehensive parasite protection. A vet prescription is required, so consult your veterinarian first. Suitable for pet owners comfortable managing monthly medications. Alternatives include topical treatments or generic oral preventives, but Credelio Plus offers broader coverage. Ideal for those prioritizing convenience and efficacy over cost.

How it compares: Credelio Plus outperforms basic flea chews by adding heartworm prevention and broader tick control. Compared to topical treatments, it avoids skin residue and is easier to administer. It's more effective than many over-the-counter options but requires a prescription and has a higher price point.

Are There Active Pet Express Trading Company Coupons for This Product?

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Enjoy 12% Discount on All Pet Supplies Products for Labor Day Sale Plus Free Shipping! Use Coupon: CPC12ON

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12% Off ⚠️ Unverified
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Best Deal for Labor Day Sale Plus Extra 12% Off & Free Shipping on All Orders in Us! Use Coupon: CPC12ON

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Frequently Asked Questions

What does Credelio Plus protect against?

Credelio Plus protects dogs from fleas, multiple tick species, and prevents heartworm disease. It also treats and controls mites, including those causing mange. Monthly use ensures continuous protection year-round.

Does Credelio Plus require a prescription?

Yes, Credelio Plus requires a veterinarian's prescription. It is a prescription-only medication due to its active ingredients and the need for proper dosing based on your dog's health and weight.

How often should I give Credelio Plus to my dog?

Administer one chew every 30 days. Consistent monthly dosing is essential for continuous protection against fleas, ticks, and heartworms, especially in high-risk environments.

Is Credelio Plus safe for all large dogs?

Credelio Plus is safe for dogs 22-45kg and at least 8 weeks old. It should not be used in dogs with a history of seizures or sensitivity to its ingredients. Consult your vet first.

Can I buy Credelio Plus without a vet visit?

No, a valid prescription is required. You must consult a licensed veterinarian before purchasing Credelio Plus, as it is a regulated veterinary medication.

How much does Credelio Plus For Extra Large Dog 22-45kg Blue 12 Chews cost?

Credelio Plus For Extra Large Dog 22-45kg Blue 12 Chews is $218.28 at Pet Express Trading Company. Prices may change — click through to Pet Express Trading Company for the latest.

Is Credelio Plus For Extra Large Dog 22-45kg Blue 12 Chews in stock at Pet Express Trading Company?

Yes, Credelio Plus For Extra Large Dog 22-45kg Blue 12 Chews is currently in stock at Pet Express Trading Company.

Are there coupon codes for Pet Express Trading Company?

Yes — Love Those Deals currently tracks 4 active Pet Express Trading Company coupons. See the coupons section on this page to copy a code before checkout.

Specifications

Brand
Credelio Plus
Product Type
Animals & Pet Supplies > Pet Supplies > Dog Supplies
Category
Animals & Pet Supplies > Pet Supplies > Dog Supplies
SKU
3915
MPN
Credelio-Plus-2498
Last updated Apr 28, 2026