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Simparica TRIO Simparica Trio For Dogs Above 88 Lbs (Brown) 6 Doses

Simparica TRIO

Simparica Trio For Dogs Above 88 Lbs (Brown) 6 Doses

Simparica Trio For Dogs Above 88 Lbs (Brown) 6 Doses is a vet-recommended chewable tablet that protects large dogs from fleas, ticks, and mites. Priced at $138.49, it offers 6 months of monthly prevention for dogs over 88 lbs, ideal for year-round parasite control.

$138.49

● In stock

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Price and availability may change. Click to see current details on BestVetCare.

Key features

  • Broad-spectrum parasite protection
  • Beef-flavored chew for easy dosing
  • Monthly oral treatment for 6 months
  • For dogs over 88 lbs
  • Targets fleas, ticks, and mites
  • Prevents heartworm, roundworms, hookworms
  • Prescription-based veterinary solution

Pros

  • +Covers multiple parasites in one dose
  • +High palatability with beef flavor
  • +Convenient monthly chewable format
  • +Trusted brand with vet approval
  • +No messy application like topicals
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Cons

  • Requires prescription
  • Higher upfront cost than some preventives
  • Not for dogs under 88 lbs
  • Potential side effects like vomiting

About Simparica TRIO Simparica Trio For Dogs Above 88 Lbs (Brown) 6 Doses

What is Simparica Trio For Dogs Above 88 Lbs (Brown) 6 Doses?

Simparica Trio For Dogs Above 88 Lbs (Brown) 6 Doses is a prescription chewable tablet designed to protect large dogs from a broad spectrum of parasites. Each dose provides one month of protection, making this 6-dose pack ideal for half a year of continuous defense. Manufactured by Zoetis, Simparica Trio combines three active ingredients—sarolaner, moxidectin, and pyrantel—to target fleas, ticks, heartworm larvae, roundworms, and hookworms. It's formulated specifically for dogs weighing over 88 lbs and comes in a brown, beef-flavored chew for easy administration.

Key features

  • Broad-Spectrum Protection — Targets fleas, ticks, heartworm, roundworms, and hookworms in one monthly dose.
  • Beef-Flavored Chew — Palatable brown tablet that most dogs accept easily, reducing administration stress.
  • Monthly Oral Treatment — Convenient chewable form eliminates the mess of topical solutions.
  • For Large Dogs — Specifically dosed for dogs over 88 lbs to ensure safety and efficacy.
  • Vet-Recommended — Trusted brand developed by Zoetis, a leader in animal health.
  • 6-Month Supply — Pack of 6 doses supports consistent, uninterrupted parasite prevention.
  • Prescription Required — Ensures proper use under veterinary supervision for optimal pet health.

Who is Simparica Trio For Dogs Above 88 Lbs (Brown) 6 Doses for?

This product is designed for owners of large breed dogs—such as Labradors, German Shepherds, or Great Danes—seeking reliable, year-round parasite protection. It’s ideal for pet parents who prefer oral medications over topical treatments and want a single solution that covers multiple threats. It's especially beneficial in regions with high tick or heartworm prevalence. A prescription is required, so it's best suited for pet owners with access to veterinary care.

How does Simparica Trio For Dogs Above 88 Lbs (Brown) 6 Doses compare?

Compared to standard flea and tick chews that only target external parasites, Simparica Trio offers added protection against heartworm, roundworms, and hookworms—making it a more comprehensive alternative to single-purpose preventives. It stands out from topical treatments by eliminating skin residue and bathing restrictions. While similar to other combination preventives, its beefy chew format is often more appealing than pills. However, it requires a prescription, unlike some over-the-counter options, which may limit accessibility for some pet owners.

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Best use cases

  • Year-round flea and tick prevention
  • Heartworm protection in high-risk areas
  • Monthly deworming for large dogs
  • Alternative to messy topical treatments
  • Veterinary-recommended parasite control
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Is Simparica Trio For Dogs Above 88 Lbs (Brown) 6 Doses right for you?

Simparica Trio is best for owners of large dogs over 88 lbs seeking comprehensive parasite protection. It requires a prescription, so veterinary access is essential. Ideal for pet parents who prefer oral chews over topicals. Alternatives include other combination preventives like Sentinel or standalone flea/tick treatments, but Simparica Trio offers broader coverage. Always consult your vet before switching treatments.

How it compares: Simparica Trio offers broader protection than flea-and-tick-only chews and eliminates the residue of topical treatments. It matches other combination preventives but with higher palatability. Requires a prescription, unlike some OTC options, but ensures safer, vet-monitored use.

Are There Active BestVetCare Coupons for This Product?

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Frequently Asked Questions

What does Simparica Trio protect against?

Simparica Trio protects dogs from fleas, ticks, mites, heartworm larvae, roundworms, and hookworms. It’s a broad-spectrum preventive that combines three active ingredients to target both external and internal parasites, making it ideal for comprehensive monthly protection.

Does Simparica Trio require a prescription?

Yes, Simparica Trio requires a prescription from a licensed veterinarian. This ensures the medication is safe for your dog, especially since it prevents heartworm. Your vet will confirm your dog’s weight and health status before approving the treatment.

How do you administer Simparica Trio?

Give one chewable tablet orally once a month, preferably with food. The beef-flavored chew is designed to be palatable, so most dogs take it willingly. Administer on the same day each month for consistent protection.

Is Simparica Trio safe for all dogs?

Simparica Trio is safe for dogs over 88 lbs and 8 weeks of age. It’s not recommended for dogs with a history of seizures. Always consult your vet before starting, especially if your dog is on other medications.

Can I buy Simparica Trio without a vet visit?

No, you cannot legally purchase Simparica Trio without a prescription. A vet must first examine your dog and confirm it’s healthy enough for heartworm prevention. Some online pharmacies offer telehealth consultations to streamline the process.

How much does Simparica Trio For Dogs Above 88 Lbs (Brown) 6 Doses cost?

Simparica Trio For Dogs Above 88 Lbs (Brown) 6 Doses is $138.49 at BestVetCare. Prices may change — click through to BestVetCare for the latest.

Is Simparica Trio For Dogs Above 88 Lbs (Brown) 6 Doses in stock at BestVetCare?

Yes, Simparica Trio For Dogs Above 88 Lbs (Brown) 6 Doses is currently in stock at BestVetCare.

Are there coupon codes for BestVetCare?

Yes — Love Those Deals currently tracks 4 active BestVetCare coupons. See the coupons section on this page to copy a code before checkout.

Specifications

Brand
Simparica TRIO
Product Type
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
Category
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
SKU
3913
GTIN
87219131619
MPN
Zoetis-Simparica-TRIO-2077
Last updated Apr 28, 2026