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Simparica TRIO Simparica Trio For Dogs 5.6-11 Lbs (Purple) 6 Doses

Simparica TRIO

Simparica Trio For Dogs 5.6-11 Lbs (Purple) 6 Doses

Simparica Trio For Dogs 5.6-11 Lbs (Purple) 6 Doses is a vet-recommended chewable tablet that protects small dogs against fleas, ticks, and mites. Priced at $68.20, it offers 6 months of monthly protection for dogs weighing 5.6–11 lbs.

$68.20

● In stock

Buy at BestVetCare →

Price and availability may change. Click to see current details on BestVetCare.

Key features

  • Triple parasite protection: fleas, ticks, heartworm
  • Fast-acting: kills fleas in 4 hours, ticks in 8
  • Beef-flavored chewable for easy administration
  • 6-month supply for small dogs 5.6–11 lbs
  • FDA-approved, vet-recommended formulation
  • Prevents hookworm, roundworm, and mange mites
  • Prescription-based for safe, targeted use

Pros

  • +Comprehensive protection in one monthly dose
  • +Fast flea and tick kill time
  • +Palatable chew, no mess application
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Cons

  • Requires prescription
  • Not for dogs with seizure history

About Simparica TRIO Simparica Trio For Dogs 5.6-11 Lbs (Purple) 6 Doses

What is Simparica Trio For Dogs 5.6-11 Lbs (Purple) 6 Doses?

Simparica Trio For Dogs 5.6-11 Lbs (Purple) 6 Doses is a monthly chewable tablet designed for small dogs, providing broad-spectrum protection against fleas, ticks, mange mites, and heartworm disease. Each pack contains six doses, offering half a year of continuous defense in an easy-to-administer, beef-flavored chew. Manufactured by Zoetis, Simparica Trio is FDA-approved and recommended by veterinarians for dogs weighing between 5.6 and 11 pounds. Available through authorized retailers like BestVetCare, this purple-labeled formulation ensures accurate dosing for small breeds.

Key features

  • Triple Protection — Targets fleas, ticks, and mites while also preventing heartworm, hookworm, and roundworm infections.
  • Monthly Chewable — Beef-flavored tablets are palatable and easy to administer once a month.
  • Fast-Acting — Starts killing fleas within 4 hours and ticks within 8 hours of administration.
  • 6-Dose Supply — Provides protection for 6 consecutive months, reducing the need for frequent reordering.
  • Small Dog Formulation — Specifically dosed for dogs 5.6–11 lbs, minimizing risk of overdose.
  • Prescription-Based — Requires veterinary approval to ensure safe and appropriate use.
  • Trusted Brand — Developed by Zoetis, a leading animal health company with clinical backing.

Who is Simparica Trio For Dogs 5.6-11 Lbs (Purple) 6 Doses for?

This product is ideal for owners of small breed dogs—such as Chihuahuas, Toy Poodles, or Yorkshire Terriers—living in areas with high flea and tick exposure. It’s suited for dogs 8 weeks of age and older, weighing 5.6 to 11 pounds. Pet owners seeking a convenient, once-a-month oral solution that also prevents intestinal parasites and heartworm will find this formulation beneficial. It’s especially valuable in warm climates or during peak tick seasons.

How does Simparica Trio For Dogs 5.6-11 Lbs (Purple) 6 Doses compare?

Compared to topical flea and tick treatments, Simparica Trio eliminates messy application and avoids skin residue. Unlike some oral preventives that only target fleas or heartworm, this product offers comprehensive protection across multiple parasites. It acts faster than many chewables and doesn’t require fasting. While similar to other combination preventives, Simparica Trio stands out for its rapid kill time and broad coverage, though it may be more expensive than single-purpose options. It is not suitable for dogs with a history of seizures, a limitation shared with other isoxazoline-class drugs.

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Best use cases

  • Monthly flea and tick prevention
  • Heartworm protection in endemic areas
  • Small breed parasite control
  • Warm climate parasite defense
  • Convenient oral alternative to topicals
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Is Simparica Trio For Dogs 5.6-11 Lbs (Purple) 6 Doses right for you?

Simparica Trio is best for owners of small dogs (5.6–11 lbs) seeking a vet-approved, all-in-one parasite preventive. It requires a prescription, so consult your veterinarian first. Ideal for pet parents who prefer oral chews over messy topicals. Alternatives include NexGard, Bravecto, or topical solutions, but Simparica Trio offers broader coverage.

How it compares: Simparica Trio offers faster flea kill and broader coverage than standard polypropylene rugs or single-target preventives. It outperforms many oral and topical treatments by combining heartworm, intestinal worm, and external parasite control in one chew.

Are There Active BestVetCare Coupons for This Product?

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Frequently Asked Questions

What does Simparica Trio protect against?

Simparica Trio protects dogs from fleas, ticks, heartworm, roundworm, hookworm, and mange mites. It’s a broad-spectrum preventive ideal for comprehensive parasite control in small dogs weighing 5.6–11 lbs.

Does Simparica Trio require a prescription?

Yes, Simparica Trio requires a prescription from a licensed veterinarian. This ensures the medication is safe and appropriate for your dog’s weight, age, and health history.

How quickly does Simparica Trio work?

Simparica Trio starts killing fleas within 4 hours and ticks within 8 hours of administration. It maintains protection for a full 30 days with monthly dosing.

Is Simparica Trio safe for small dogs?

Yes, the purple 5.6–11 lb formulation is specifically dosed for small breeds. It’s safe for dogs 8 weeks and older, but not recommended for dogs with a history of seizures.

Can I buy Simparica Trio without a vet visit?

No, Simparica Trio requires a valid prescription. You must have a veterinarian-client-patient relationship to purchase it, even from online retailers like BestVetCare.

How much does Simparica Trio For Dogs 5.6-11 Lbs (Purple) 6 Doses cost?

Simparica Trio For Dogs 5.6-11 Lbs (Purple) 6 Doses is $68.20 at BestVetCare. Prices may change — click through to BestVetCare for the latest.

Is Simparica Trio For Dogs 5.6-11 Lbs (Purple) 6 Doses in stock at BestVetCare?

Yes, Simparica Trio For Dogs 5.6-11 Lbs (Purple) 6 Doses is currently in stock at BestVetCare.

Are there coupon codes for BestVetCare?

Yes — Love Those Deals currently tracks 4 active BestVetCare coupons. See the coupons section on this page to copy a code before checkout.

Specifications

Brand
Simparica TRIO
Product Type
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
Category
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
SKU
3913
GTIN
87219131626
MPN
Zoetis-Simparica-TRIO-2065
Last updated Apr 28, 2026