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Simparica TRIO Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses

Simparica TRIO

Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses

Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses is a vet-recommended oral chewable that prevents fleas, ticks, and heartworms in large dogs. Priced at $58.30, it's ideal for pet owners seeking reliable, monthly protection with minimal effort and fast-acting ingredients.

$58.30

● In stock

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Price and availability may change. Click to see current details on BestVetCare.

Key features

  • Triple protection against fleas, ticks, and heartworms
  • Starts killing fleas within 4 hours
  • Controls 6 tick species including deer and brown dog ticks
  • Monthly chewable tablet for easy dosing
  • For dogs 44.1–88 lbs (green pack)
  • Prescription required for purchase
  • 3-dose pack provides 3 months of protection

Pros

  • +Fast-acting flea and tick control
  • +Convenient monthly dosing
  • +Backed by veterinary approval
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Cons

  • Requires prescription
  • Not for dogs under 44.1 lbs

About Simparica TRIO Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses

What is Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses?

Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses is a prescription-strength, chewable tablet designed for large dogs weighing between 44.1 and 88 pounds. Manufactured by Zoetis, this monthly treatment effectively prevents heartworm disease, kills fleas, and controls multiple tick species including black-legged, American, and brown dog ticks. Each pack contains three doses, providing three months of continuous protection. The green-colored chews are formulated for palatability, making administration easier for pet owners.

Key features

  • Triple Protection — Prevents heartworm, kills fleas, and controls six types of ticks.
  • Fast-Acting Formula — Starts killing fleas within 4 hours and ticks within 8 hours.
  • Monthly Chewable — Easy-to-administer oral tablet with no mess or residue.
  • For Large Dogs — Specifically dosed for dogs 44.1–88 lbs (green pack).
  • Prescription-Based — Requires veterinarian approval for purchase.
  • Three-Month Supply — Includes 3 full doses for uninterrupted protection.
  • Trusted Brand — From Zoetis, a leading animal health manufacturer.

Who is Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses for?

This product is ideal for owners of large dogs living in areas with high flea and tick exposure or seasonal heartworm risk. It suits pet parents seeking a convenient, once-a-month solution that doesn’t involve topical applications. Dogs must be at least 8 weeks old and under veterinary care to use this medication safely.

How does Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses compare?

Compared to standard polypropylene rugs or fixed overhead cranes, Simparica Trio serves a completely different purpose—targeting parasitic threats in pets. Unlike basic flea collars or short-duration sprays, it offers comprehensive, systemic protection for a full month. It outperforms many over-the-counter chews by targeting more tick species and providing heartworm prevention in one dose. While similar to other prescription chews, Simparica Trio stands out for its rapid kill time and broad-spectrum coverage.

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Best use cases

  • Monthly flea prevention for large dogs
  • Tick control in wooded or grassy areas
  • Heartworm prevention in high-risk regions
  • Alternative to messy topical treatments
  • Year-round parasite protection
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Is Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses right for you?

Simparica Trio is best for dog owners with large breeds needing reliable, vet-approved parasite protection. No special skills needed—just administer monthly. Alternatives include topical treatments or collars, but this chew offers faster, cleaner coverage. Always consult your vet before switching treatments.

How it compares: Simparica Trio offers faster flea kill and broader tick control than many OTC chews, plus heartworm prevention. It’s more convenient than messy topicals and more effective than basic flea collars for large dogs in high-exposure areas.

Are There Active BestVetCare Coupons for This Product?

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20% Off ⚠️ Unverified
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Summer Must-haves for Pets €“ 20% OFF Heartworm Prevention + Free Shipping*

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20% Off ⚠️ Unverified
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Frequently Asked Questions

What does Simparica Trio protect against?

Simparica Trio protects dogs from fleas, six types of ticks, and prevents heartworm disease. It also treats and controls demodectic mange and sarcoptic mange in dogs over 8 weeks old.

Does Simparica Trio require a prescription?

Yes, Simparica Trio requires a valid prescription from a licensed veterinarian. It is a prescription-only medication to ensure safe and appropriate use for your dog.

How quickly does Simparica Trio work?

Simparica Trio starts killing fleas within 4 hours and ticks within 8 hours of administration. It provides continuous protection for a full month after each dose.

Is Simparica Trio safe for all dogs?

Simparica Trio is safe for dogs 8 weeks and older weighing 44.1–88 lbs. It should not be used in dogs with a history of seizures or neurological disorders without vet approval.

Can I buy Simparica Trio without a vet visit?

No, you must have a prescription to purchase Simparica Trio. Some online pharmacies allow remote vet consultations to obtain the required prescription.

How much does Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses cost?

Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses is $58.30 at BestVetCare. Prices may change — click through to BestVetCare for the latest.

Is Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses in stock at BestVetCare?

Yes, Simparica Trio For Dogs 44.1-88 Lbs (Green) 3 Doses is currently in stock at BestVetCare.

Are there coupon codes for BestVetCare?

Yes — Love Those Deals currently tracks 4 active BestVetCare coupons. See the coupons section on this page to copy a code before checkout.

Specifications

Brand
Simparica TRIO
Product Type
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
Category
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
SKU
3913
MPN
Zoetis-Simparica-TRIO-2073
Last updated Apr 28, 2026