10% Off ⚠️ Unverified
Expires Jun 4 Set Auto-order & Get Extra 10% Discount
••••••••
We earn a commission if you shop through this link.
Simparica TRIO
Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses
Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses is a vet-recommended chewable tablet that protects large dogs against fleas, ticks, and heartworms. Priced at $217.69, it offers year-round parasite defense with monthly dosing for dogs weighing 44.1 to 88 lbs.
$217.69
● In stock
Buy at BestVetCare →Price and availability may change. Click to see current details on BestVetCare.
★
Key features
- Triple-Action Protection — Combats fleas, ticks, and heartworms
- Fast-Acting Formula — Kills fleas in 4 hours, ticks in 8 hours
- Convenient Chewable — Palatable tablet, no food required
- Year-Round Coverage — 12 monthly doses included
- Prescription-Based — Ensures safe, vet-approved use
- Weight-Specific Dosing — For dogs 44.1–88 lbs
- Green Packaging — Easy dose identification
✓
Pros
- +Comprehensive parasite protection in one dose
- +Fast flea and tick kill times
- +Easy to administer chewable form
- +Full year supply with consistent dosing
- +Veterinarian-recommended formula
!
Cons
- −Requires prescription, not over-the-counter
- −Higher cost than single-target treatments
- −Not for dogs under 44.1 lbs or 8 weeks old
ℹ
About Simparica TRIO Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses
What is Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses?
Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses is a prescription chewable tablet designed for large dogs, providing comprehensive protection against multiple parasites. Each dose targets fleas, ticks, mange mites, and prevents heartworm disease. Administered once a month, this 12-dose pack ensures a full year of consistent, reliable parasite control. Sold by BestVetCare, it's priced at $217.69 with free shipping and is suitable for dogs weighing between 44.1 and 88 pounds.
Key features
- Triple-Action Protection — Combats fleas, ticks, and heartworms in one monthly dose.
- Fast-Acting Formula — Starts killing fleas within 4 hours and ticks within 8 hours.
- Convenient Chewable — Palatable tablet that most dogs accept easily without food.
- Year-Round Coverage — 12-dose supply supports uninterrupted monthly treatment.
- Prescription-Based — Requires veterinarian approval for safe and targeted use.
- Weight-Specific Dosing — Formulated for dogs 44.1–88 lbs to ensure efficacy and safety.
- Green Packaging — Color-coded for easy identification of correct dosage size.
Who is Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses for?
This product is ideal for dog owners with large breeds weighing 44.1 to 88 pounds who need reliable, monthly parasite prevention. It’s especially beneficial for pets in regions with high tick and flea activity or those frequently exposed to outdoor environments. It’s not suitable for dogs under 44.1 lbs or under 8 weeks of age. Always consult a veterinarian before starting treatment.
How does Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses compare?
Compared to single-target treatments, Simparica Trio offers broader protection in one tablet, reducing the need for multiple medications. It acts faster than many oral flea and tick preventives and provides heartworm prevention, which topical treatments lack. While more expensive than basic flea collars or generic chews, its triple-action formula and proven efficacy make it a premium choice for comprehensive care.
🎯
Best use cases
- →Monthly flea and tick prevention
- →Heartworm disease prevention
- →Year-round parasite control for large dogs
- →Dogs in high tick exposure areas
- →Owners seeking all-in-one protection
🛒
Is Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses right for you?
Simparica Trio is best for owners of large dogs (44.1–88 lbs) seeking comprehensive, vet-approved parasite protection. No special skill needed—just monthly administration. Alternatives include single-target chews or topical treatments, but they lack combined coverage. Always confirm with your vet before switching.
How it compares: Simparica Trio outperforms standard flea chews and topical treatments by combining heartworm prevention with rapid flea and tick control, offering broader protection than single-mechanism products.
Are There Active BestVetCare Coupons for This Product?
30% Off ⚠️ Unverified
Expires Jun 4 Hop into Spring Deals - 30% OFF Flea & Tick Treatments + Free Shipping!
••••••••
We earn a commission if you shop through this link.
20% Off ⚠️ Unverified
Expires Jun 4 Summer Must-haves for Pets  20% OFF Heartworm Prevention + Free Shipping*
••••••••
We earn a commission if you shop through this link.
20% Off ⚠️ Unverified
Expires May 31 Summer Must-Haves for Pets â 20% OFF Heartworm Prevention + Free Shipping*
••••••••
We earn a commission if you shop through this link.
More from BestVetCare
🛍️
Bravecto Spot On
20 Inch | Wigfever Highlight Silky Straight 7*4 Wear Go Pre Cut
$110.60🛍️
Effipro DUO
24 Inch | Wigfever 360 Silky Straight Invisi DrawString Wear Go
$139.40🛍️
Effipro DUO Spot-On
26 Inch | Wigfever 13x6 Silky Straight Lace Front Human Hair Wigs
$145.40🛍️
Bay-O-Pet Kiltix Collar
360 Lace Body Wave Invisi Draw String Wear Go Wig Pre-Bleached Pre-Cut
$210.00 ?
Frequently Asked Questions
What does Simparica Trio protect against?
▾
Simparica Trio protects dogs against fleas, ticks, mange mites, and prevents heartworm disease. It’s a triple-action formula designed for comprehensive parasite control in one monthly chewable dose.
Does Simparica Trio require a prescription?
▾
Yes, Simparica Trio requires a prescription from a licensed veterinarian. This ensures safe and appropriate use based on your dog’s weight, age, and health condition.
How quickly does Simparica Trio kill fleas?
▾
Simparica Trio starts killing fleas within 4 hours of administration and eliminates 100% of fleas within 12 hours. It also kills ticks within 8 hours, offering fast-acting protection.
Is Simparica Trio safe for all dogs?
▾
Simparica Trio is safe for dogs weighing 44.1–88 lbs and aged 8 weeks or older. It is not recommended for smaller dogs or puppies under 8 weeks. Consult your vet before use.
Can I buy Simparica Trio without a vet visit?
▾
No, you cannot buy Simparica Trio without a prescription. A valid vet prescription is required to purchase this product, even online through retailers like BestVetCare.
How much does Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses cost?
▾
Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses is $217.69 at BestVetCare. Prices may change — click through to BestVetCare for the latest.
Is Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses in stock at BestVetCare?
▾
Yes, Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Doses is currently in stock at BestVetCare.
Are there coupon codes for BestVetCare?
▾
Yes — Love Those Deals currently tracks 4 active BestVetCare coupons. See the coupons section on this page to copy a code before checkout.
≡
Specifications
- Brand
- Simparica TRIO
- Product Type
- Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
- Category
- Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
- SKU
- 3913
- MPN
- Zoetis-Simparica-TRIO-2075
Last updated Apr 28, 2026