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Interceptor Plus Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Chews

Interceptor Plus

Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Chews

Interceptor Plus Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Chews is a vet-recommended, broad-spectrum parasite protection chew priced at $219.89. It prevents heartworm, kills fleas and ticks, and treats intestinal worms in medium to large dogs.

$219.89

● In stock

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Price and availability may change. Click to see current details on BestVetCare.

Key features

  • Broad-spectrum parasite protection
  • Beef-flavored chew for easy dosing
  • Contains milbemycin oxime, praziquantel, sarolaner
  • Monthly administration
  • For dogs 44.1–88 lbs (green chew)
  • Prevents heartworm, treats intestinal worms
  • Kills fleas and ticks

Pros

  • +All-in-one parasite protection
  • +High palatability, most dogs eat willingly
  • +Vet-approved and clinically effective
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Cons

  • Higher price point than basic preventatives
  • Not for dogs under 44.1 lbs

About Interceptor Plus Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Chews

What is Interceptor Plus Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Chews?

Interceptor Plus Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Chews is a monthly oral medication designed for medium to large dogs weighing between 44.1 and 88 pounds. This combination chew offers comprehensive protection against a wide range of parasites, including heartworms, roundworms, hookworms, whipworms, fleas, and ticks. Formulated with the active ingredients milbemycin oxime, praziquantel, and sarolaner, it delivers triple-action defense in a single, beef-flavored tablet that most dogs readily accept. Administered once a month, it simplifies parasite prevention for pet owners seeking reliable, all-in-one protection.

Key features

  • Broad-Spectrum Protection — Targets heartworms, fleas, ticks, roundworms, hookworms, whipworms, and tapeworms.
  • Beef-Flavored Chew — Palatable formula makes monthly dosing easier for most dogs.
  • Vet-Recommended Formula — Contains milbemycin oxime, praziquantel, and sarolaner for proven efficacy.
  • Monthly Dosage — One chew every 30 days provides continuous protection.
  • For Dogs 44.1–88 lbs — Green chew specifically dosed for medium to large breeds.
  • Prevents Heartworm Disease — Kills larvae before they mature into adult heartworms.
  • Kills Ticks — Effective against multiple tick species including black-legged and American dog ticks.

Who is Interceptor Plus Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Chews for?

This product is ideal for dog owners with medium to large breeds—such as Border Collies, Australian Shepherds, or Bulldogs—weighing between 44.1 and 88 pounds. It’s especially beneficial for pets exposed to outdoor environments where fleas, ticks, and internal parasites are common. Veterinarians often recommend it for dogs needing a single, convenient chew that replaces multiple preventatives. It’s not intended for dogs under 44.1 lbs or under 8 weeks of age.

How does Interceptor Plus Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Chews compare?

Compared to standalone heartworm preventatives or flea-and-tick treatments, Simparica Trio offers a more comprehensive solution by combining three medications in one chew. It eliminates the need for separate dewormers or monthly topical applications. Unlike standard polypropylene rugs or fixed overhead cranes, this product serves a highly specific health purpose with clinical backing. While pricier than basic heartworm chews, its all-in-one action can reduce long-term costs and improve compliance. It stands out among parasite preventatives for medium-large dogs needing full-spectrum coverage.

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Best use cases

  • Monthly heartworm prevention
  • Flea and tick control in outdoor dogs
  • Treatment of roundworm and hookworm
  • Integrated parasite management
  • Veterinary-recommended prevention plan
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Is Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Chews right for you?

Ideal for owners of medium to large dogs needing comprehensive parasite protection. No special skills required—just monthly dosing. Consider if your dog is exposed to ticks or unclean environments. Alternatives include separate heartworm and flea treatments, but Simparica Trio offers convenience and broader coverage.

How it compares: Compared to single-purpose heartworm chews or topical flea treatments, Simparica Trio provides broader protection in one dose. It reduces the need for multiple medications, improving compliance and coverage for dogs in high-risk environments.

Are There Active BestVetCare Coupons for This Product?

10% Off ⚠️ Unverified
Expires Jun 4
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Set Auto-order & Get Extra 10% Discount

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30% Off ⚠️ Unverified
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Hop into Spring Deals - 30% OFF Flea & Tick Treatments + Free Shipping!

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20% Off ⚠️ Unverified
Expires Jun 4
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Summer Must-haves for Pets €“ 20% OFF Heartworm Prevention + Free Shipping*

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20% Off ⚠️ Unverified
Expires May 31
BestVetCare

Summer Must-Haves for Pets – 20% OFF Heartworm Prevention + Free Shipping*

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Frequently Asked Questions

What does Interceptor Plus Simparica Trio protect against?

It prevents heartworm disease and treats infections from roundworms, hookworms, whipworms, and tapeworms. It also kills fleas and ticks, including black-legged and American dog ticks, in dogs weighing 44.1–88 lbs.

Does Simparica Trio require a prescription?

Yes, Interceptor Plus Simparica Trio requires a veterinarian's prescription. It's a prescription-only medication due to its active ingredients and intended use in preventing serious parasitic diseases.

How often should I give this chew to my dog?

Administer one chew every 30 days. Monthly dosing ensures continuous protection against heartworms, fleas, ticks, and intestinal parasites. Consistency is key for maximum effectiveness.

Is the green chew safe for all dog breeds?

The green chew is safe for dogs weighing 44.1–88 lbs and aged 8 weeks or older. It is not recommended for smaller dogs or puppies under 8 weeks due to dosage requirements.

Can I split the chew for a smaller dog?

No, do not split the chew. The green chew is dosed specifically for 44.1–88 lb dogs. Splitting may result in incorrect dosing and reduced effectiveness. Use the appropriate weight-specific product instead.

How much does Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Chews cost?

Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Chews is $219.89 at BestVetCare. Prices may change — click through to BestVetCare for the latest.

Is Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Chews in stock at BestVetCare?

Yes, Simparica Trio For Dogs 44.1-88 Lbs (Green) 12 Chews is currently in stock at BestVetCare.

Are there coupon codes for BestVetCare?

Yes — Love Those Deals currently tracks 4 active BestVetCare coupons. See the coupons section on this page to copy a code before checkout.

Specifications

Brand
Interceptor Plus
Product Type
Animals & Pet Supplies > Pet Supplies > Dog Supplies
Category
Animals & Pet Supplies > Pet Supplies > Dog Supplies
SKU
3913
GTIN
716688241412
MPN
Elanco-Interceptor-Plus-2420
Last updated Apr 28, 2026