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Interceptor Plus Simparica Trio For Dogs 22.1-44 Lbs (Blue) 6 Chews

Interceptor Plus

Simparica Trio For Dogs 22.1-44 Lbs (Blue) 6 Chews

Interceptor Plus Simparica Trio For Dogs 22.1-44 Lbs (Blue) 6 Chews is a vet-recommended chewable parasite protection for medium dogs, priced at $85.89. Prevents heartworm, kills fleas, ticks, and intestinal worms in one monthly dose.

$85.89

● In stock

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Price and availability may change. Click to see current details on BestVetCare.

Key features

  • Triple parasite protection: heartworm, fleas, ticks, and intestinal worms
  • Monthly beef-flavored chew for dogs 22.1–44 lbs
  • Kills fleas and multiple tick species including Lyme carriers
  • Prevents heartworm disease and controls roundworms, hookworms
  • Vet-recommended formula with proven active ingredients
  • Easy administration with high palatability
  • Color-coded blue for correct dosage identification

Pros

  • +Comprehensive protection in one monthly dose
  • +Highly palatable beef flavor dogs enjoy
  • +Kills fleas before they lay eggs
  • +Effective against multiple tick species
  • +Reduces need for multiple parasite treatments
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Cons

  • Higher price point than basic heartworm preventives
  • Not recommended for dogs with seizure history
  • Requires monthly administration for full protection
  • May cause gastrointestinal upset in sensitive dogs

About Interceptor Plus Simparica Trio For Dogs 22.1-44 Lbs (Blue) 6 Chews

What is Interceptor Plus Simparica Trio For Dogs 22.1-44 Lbs (Blue) 6 Chews?

Interceptor Plus Simparica Trio For Dogs 22.1-44 Lbs (Blue) 6 Chews is a monthly oral treatment designed for medium-sized dogs weighing between 22.1 and 44 pounds. This dual-action formula combines milbemycin oxime and praziquantel from Interceptor Plus with sarolaner from Simparica to deliver broad-spectrum protection against multiple parasites. It prevents heartworm disease, controls roundworms, hookworms, whipworms, and tapeworms, while also killing fleas and ticks, including black-legged, American dog, and lone star ticks. Administered once a month, this beef-flavored chew ensures ease of dosing and high palatability.

Key features

  • Triple Parasite Protection — Targets heartworms, intestinal worms, fleas, and ticks in one chew.
  • Monthly Dosage — Simple, once-a-month administration for consistent protection.
  • Beef-Flavored Chew — Palatable formula dogs accept easily, reducing resistance.
  • For Medium Dogs — Specifically formulated for dogs 22.1–44 lbs, color-coded blue for easy identification.
  • Vet-Recommended — Trusted by veterinarians for comprehensive parasite control.
  • Kills Ticks — Effective against multiple tick species known to transmit Lyme and other diseases.
  • Prevents Heartworm Disease — Stops heartworm larvae before they mature into adult worms.

Who is Interceptor Plus Simparica Trio For Dogs 22.1-44 Lbs (Blue) 6 Chews for?

This product is ideal for dog owners seeking a reliable, all-in-one parasite prevention solution for medium-sized dogs. It’s especially beneficial for pets exposed to outdoor environments where fleas, ticks, and intestinal parasites are common. Veterinarians often recommend it for dogs in regions with high heartworm prevalence. It’s suitable for dogs 6 months and older, but consultation with a vet is advised for dogs with seizure history, as sarolaner may not be appropriate for all animals.

How does Interceptor Plus Simparica Trio For Dogs 22.1-44 Lbs (Blue) 6 Chews compare?

Compared to standard polypropylene rugs, fixed overhead cranes, or basic flea collars, this chew offers advanced, systemic protection that works from the inside out. Unlike topical treatments or single-target preventives, Simparica Trio delivers combined action against internal and external parasites. It outperforms standalone heartworm preventives by adding flea and tick control, reducing the need for multiple products. While more expensive than generic heartworm chews, its broad coverage offers convenience and enhanced protection for at-risk dogs.

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Best use cases

  • Monthly heartworm prevention for medium dogs
  • Flea and tick control in tick-prone regions
  • Deworming for roundworms and hookworms
  • Preventive care for dogs with outdoor access
  • Veterinarian-recommended parasite protection
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Is Simparica Trio For Dogs 22.1-44 Lbs (Blue) 6 Chews right for you?

Dog owners with medium-sized pets (22.1–44 lbs) should consider this chew for comprehensive parasite protection. No special skills needed—just monthly dosing. Ideal for those replacing separate heartworm, flea, and deworming treatments. Alternatives include standalone preventives or topical solutions, but this offers broader coverage.

How it compares: Compared to basic heartworm chews or flea collars, Interceptor Plus Simparica Trio offers superior broad-spectrum protection by combining internal and external parasite control in one palatable chew, reducing product clutter and improving compliance.

Are There Active BestVetCare Coupons for This Product?

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Frequently Asked Questions

What does Interceptor Plus Simparica Trio protect against?

It prevents heartworm disease, kills fleas and ticks, and controls roundworms, hookworms, whipworms, and tapeworms in dogs 22.1–44 lbs with one monthly chew.

Does Simparica Trio require a prescription?

Yes, Interceptor Plus Simparica Trio requires a veterinarian’s prescription due to its active ingredients and intended use in medical parasite prevention.

How quickly does Simparica Trio kill fleas?

Simparica Trio begins killing fleas within 4 hours and eliminates 100% of fleas within 24 hours, helping prevent infestations in your home.

Is Interceptor Plus Simparica Trio safe for all dogs?

It’s safe for most dogs 6 months and older, but should be used with caution in dogs with a history of seizures. Consult your vet before use.

Can I give this chew to my dog every month?

Yes, Interceptor Plus Simparica Trio is designed for monthly administration year-round to ensure continuous protection against heartworms, fleas, and intestinal parasites.

How much does Simparica Trio For Dogs 22.1-44 Lbs (Blue) 6 Chews cost?

Simparica Trio For Dogs 22.1-44 Lbs (Blue) 6 Chews is $85.89 at BestVetCare. Prices may change — click through to BestVetCare for the latest.

Is Simparica Trio For Dogs 22.1-44 Lbs (Blue) 6 Chews in stock at BestVetCare?

Yes, Simparica Trio For Dogs 22.1-44 Lbs (Blue) 6 Chews is currently in stock at BestVetCare.

Are there coupon codes for BestVetCare?

Yes — Love Those Deals currently tracks 4 active BestVetCare coupons. See the coupons section on this page to copy a code before checkout.

Specifications

Brand
Interceptor Plus
Product Type
Animals & Pet Supplies > Pet Supplies > Dog Supplies
Category
Animals & Pet Supplies > Pet Supplies > Dog Supplies
SKU
3913
GTIN
716688161611
MPN
Elanco-Interceptor-Plus-2416
Last updated Apr 28, 2026