Skip to content
Simparica TRIO Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 3 Doses

Simparica TRIO

Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 3 Doses

Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 3 Doses is a chewable tablet that protects dogs against fleas, ticks, and heartworm. Priced at $37.51, it's ideal for small to medium dogs needing monthly parasite control with a palatable caramel flavor.

$37.51

● In stock

Buy at BestVetCare →

Price and availability may change. Click to see current details on BestVetCare.

Key features

  • Triple parasite protection: fleas, ticks, heartworm
  • Caramel-flavored chewable tablet for easy dosing
  • Kills fleas within 4 hours, ticks within 8 hours
  • Treats and controls roundworms and hookworms
  • 3-month supply with 3 pre-measured doses
  • For dogs 11.1–22 lbs, once-monthly administration
  • Available at BestVetCare with free shipping

Pros

  • +Fast-acting against fleas and ticks
  • +Broad-spectrum parasite protection
  • +Pleasant caramel flavor dogs like
!

Cons

  • Requires prescription
  • Not for dogs under 11.1 lbs

About Simparica TRIO Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 3 Doses

What is Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 3 Doses?

Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 3 Doses is a veterinarian-recommended, once-monthly chewable tablet designed to protect dogs from multiple parasites. Formulated for small to medium-sized dogs weighing between 11.1 and 22 pounds, this treatment effectively kills fleas, ticks, and prevents heartworm disease. It also treats and controls roundworms and hookworms, offering broad-spectrum protection in a single dose. The caramel flavor makes administration easy, as most dogs accept it like a treat.

Key features

  • Triple Protection — Targets fleas, ticks, and heartworms in one monthly dose.
  • Chewable Caramel Flavor — Palatable formula dogs enjoy, reducing resistance during dosing.
  • Fast-Acting — Begins killing fleas within 4 hours and ticks within 8 hours.
  • Broad Parasite Coverage — Also treats and controls roundworms and hookworms.
  • Convenient 3-Dose Pack — Provides three months of protection for continuous care.
  • For Dogs 11.1–22 lbs — Specifically dosed for small to medium breeds.
  • Available at BestVetCare — Priced at $37.51 with free shipping and reward points.

Who is Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 3 Doses for?

This product is ideal for dog owners seeking a reliable, easy-to-administer solution for comprehensive parasite prevention. It’s best suited for owners of small to medium dogs that spend time outdoors, where exposure to fleas, ticks, and intestinal worms is more likely. Veterinarians often recommend it for year-round use in regions with high parasite prevalence.

How does Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 3 Doses compare?

Compared to standard flea and tick chews, Simparica Trio offers added protection against heartworm, roundworms, and hookworms—making it more comprehensive than single-purpose treatments. It acts faster than many topical solutions and avoids skin residue. While some generic alternatives may be cheaper, they often lack the same breadth of parasite coverage. Compared to other oral combination preventives, Simparica Trio’s fast kill time and palatable flavor give it an edge in efficacy and ease of use.

🎯

Best use cases

  • Monthly flea and tick prevention
  • Heartworm protection in high-risk areas
  • Treatment of roundworm and hookworm
  • Year-round parasite control for small dogs
  • Easy dosing for picky eaters
🛒

Is Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 3 Doses right for you?

Simparica Trio is best for owners of small to medium dogs needing comprehensive monthly parasite protection. No special skills needed—just administer once a month with food. Alternatives include topical treatments or single-target oral preventives, but Simparica Trio offers broader coverage. Always consult your vet before switching treatments.

How it compares: Simparica Trio outperforms basic flea and tick chews by adding heartworm, roundworm, and hookworm protection. It’s faster than topicals and more convenient than multi-product regimens, making it a top choice for full-spectrum parasite control in small dogs.

Are There Active BestVetCare Coupons for This Product?

10% Off ⚠️ Unverified
Expires Jun 4
BestVetCare

Set Auto-order & Get Extra 10% Discount

••••••••

We earn a commission if you shop through this link.

30% Off ⚠️ Unverified
Expires Jun 4
BestVetCare

Hop into Spring Deals - 30% OFF Flea & Tick Treatments + Free Shipping!

••••••••

We earn a commission if you shop through this link.

20% Off ⚠️ Unverified
Expires Jun 4
BestVetCare

Summer Must-haves for Pets €“ 20% OFF Heartworm Prevention + Free Shipping*

••••••••

We earn a commission if you shop through this link.

20% Off ⚠️ Unverified
Expires May 31
BestVetCare

Summer Must-Haves for Pets – 20% OFF Heartworm Prevention + Free Shipping*

••••••••

We earn a commission if you shop through this link.

More from BestVetCare

?

Frequently Asked Questions

What does Simparica Trio protect against?

Simparica Trio protects dogs from fleas, ticks, heartworm, roundworms, and hookworms. It’s a broad-spectrum preventive that combines multiple treatments into one monthly chewable tablet, making it ideal for comprehensive parasite control.

Does Simparica Trio require a prescription?

Yes, Simparica Trio requires a prescription from a licensed veterinarian. This ensures the medication is safe and appropriate for your dog’s weight, health, and parasite risk level before starting treatment.

How fast does Simparica Trio work?

Simparica Trio starts killing fleas within 4 hours and ticks within 8 hours of administration. It maintains protection for a full 30 days, making it one of the fastest-acting oral parasite preventives available.

Is Simparica Trio safe for all dogs?

Simparica Trio is safe for dogs weighing 11.1–22 lbs and at least 8 weeks old. It is not recommended for dogs with a history of seizures. Always consult your vet before use.

Can I buy Simparica Trio without a vet visit?

No, you cannot buy Simparica Trio without a prescription. However, many online pharmacies like BestVetCare offer telehealth consultations to streamline the process and deliver the medication directly to your door.

How much does Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 3 Doses cost?

Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 3 Doses is $37.51 at BestVetCare. Prices may change — click through to BestVetCare for the latest.

Is Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 3 Doses in stock at BestVetCare?

Yes, Simparica Trio For Dogs 11.1-22 Lbs (Caramel) 3 Doses is currently in stock at BestVetCare.

Are there coupon codes for BestVetCare?

Yes — Love Those Deals currently tracks 4 active BestVetCare coupons. See the coupons section on this page to copy a code before checkout.

Specifications

Brand
Simparica TRIO
Product Type
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
Category
Animals & Pet Supplies > Pet Supplies > Pet Flea & Tick Control
SKU
3913
MPN
Zoetis-Simparica-TRIO-2067
Last updated Apr 28, 2026