Skip to content
Revolution Revolution Large Dogs 40.1-85lbs (Green) 12 Doses

Revolution

Revolution Large Dogs 40.1-85lbs (Green) 12 Doses

Revolution Large Dogs 40.1-85lbs (Green) 12 Doses is a vet-recommended topical parasite treatment for large dogs, priced at $227.59. Prevents heartworm, fleas, ticks, and mites in one monthly dose.

$227.59

● In stock

Buy at BestVetCare →

Price and availability may change. Click to see current details on BestVetCare.

Key features

  • Protects against heartworm, fleas, ticks, and mites
  • Topical application, no pills required
  • 12 monthly doses for year-round coverage
  • Contains vet-approved selamectin
  • Water-resistant after 2 hours
  • Green-coded for 40.1-85 lb dogs
  • Prescription-based for safety

Pros

  • +Broad-spectrum parasite protection
  • +Easy monthly topical application
  • +Trusted by veterinarians nationwide
  • +Effective in swimming or rainy climates
  • +Reduces risk of serious diseases
!

Cons

  • Requires prescription approval
  • Higher upfront cost than OTC options
  • Not effective against all tick species
  • Must avoid shampooing for 2 hours

About Revolution Revolution Large Dogs 40.1-85lbs (Green) 12 Doses

What is Revolution Large Dogs 40.1-85lbs (Green) 12 Doses?

Revolution Large Dogs 40.1-85lbs (Green) 12 Doses is a prescription-strength, once-monthly topical solution designed for large dogs weighing between 40.1 and 85 pounds. Manufactured by Zoetis, Revolution is a trusted name in veterinary parasite control. This 12-dose pack provides a full year of protection against heartworm disease, fleas, American dog ticks, sarcoptic mange mites, and ear mites. Applied directly to the skin monthly, it offers broad-spectrum defense without the need for oral administration, making it ideal for dogs that resist pills.

Key features

  • Broad-Spectrum Protection — Targets heartworms, fleas, ticks, ear mites, and sarcoptic mange in one application.
  • Vet-Approved Formula — Contains selamectin, a clinically proven active ingredient trusted by veterinarians.
  • Monthly Topical Application — Easy-to-use pipette applied to the skin, no pills required.
  • Year-Round Coverage — 12-dose supply ensures consistent protection for 12 months.
  • Water-Resistant — Remains effective after swimming or bathing, provided the dog is not shampooed excessively.
  • Green Dose Indicator — Color-coded packaging helps prevent dosing errors for large dogs.
  • Prescription-Based — Requires veterinary approval to ensure safe and correct use.

Who is Revolution Large Dogs 40.1-85lbs (Green) 12 Doses for?

This product is ideal for owners of large dogs weighing 40.1 to 85 lbs who seek reliable, year-round parasite prevention. It’s especially beneficial for dogs in regions with high flea and tick prevalence or those frequently exposed to other dogs. Veterinarians often recommend it for dogs with sensitivities to oral medications. It’s suitable for dogs 8 weeks and older, provided they are under veterinary supervision.

How does Revolution Large Dogs 40.1-85lbs (Green) 12 Doses compare?

Compared to standard polypropylene rugs, fixed overhead cranes, or generic flea collars, Revolution offers targeted, medical-grade parasite control. Unlike over-the-counter chews or collars that may only address fleas or ticks, Revolution provides comprehensive protection including heartworm prevention—a critical difference. It stands apart from oral treatments by offering a non-invasive topical solution, beneficial for picky eaters. While more expensive than some OTC options, its vet-backed efficacy and broad coverage justify the cost for proactive pet owners.

🎯

Best use cases

  • Monthly heartworm prevention
  • Flea and tick control in warm climates
  • Managing ear mite infestations
  • Preventing mange in multi-dog homes
  • Non-oral treatment for pill-averse dogs
🛒

Is Revolution Large Dogs 40.1-85lbs (Green) 12 Doses right for you?

This product is best for owners of large dogs (40.1–85 lbs) seeking reliable, vet-backed parasite protection. No special skills needed—just apply monthly to the skin. Requires a prescription, so consult your vet first. Alternatives include oral chews like NexGard or Bravecto, but Revolution offers broader coverage including heartworm and mites.

How it compares: Revolution provides broader protection than flea collars or oral chews, including heartworm prevention and mite control. Unlike fixed overhead cranes or standard polypropylene rugs, it's a medical treatment with specific dosing. It's more comprehensive than OTC options but requires a prescription.

Are There Active BestVetCare Coupons for This Product?

10% Off ⚠️ Unverified
Expires Jun 4
BestVetCare

Set Auto-order & Get Extra 10% Discount

••••••••

We earn a commission if you shop through this link.

30% Off ⚠️ Unverified
Expires Jun 4
BestVetCare

Hop into Spring Deals - 30% OFF Flea & Tick Treatments + Free Shipping!

••••••••

We earn a commission if you shop through this link.

20% Off ⚠️ Unverified
Expires Jun 4
BestVetCare

Summer Must-haves for Pets €“ 20% OFF Heartworm Prevention + Free Shipping*

••••••••

We earn a commission if you shop through this link.

20% Off ⚠️ Unverified
Expires May 31
BestVetCare

Summer Must-Haves for Pets – 20% OFF Heartworm Prevention + Free Shipping*

••••••••

We earn a commission if you shop through this link.

More from BestVetCare

?

Frequently Asked Questions

What does Revolution for large dogs protect against?

Revolution protects large dogs from heartworm disease, fleas, American dog ticks, ear mites, and sarcoptic mange. It's a broad-spectrum treatment applied monthly to the skin and is effective in preventing multiple parasites with one dose.

Does Revolution require a prescription?

Yes, Revolution requires a prescription from a licensed veterinarian. This ensures the medication is safe for your dog’s health status and weight, and helps prevent misuse or adverse reactions in sensitive animals.

How do you apply Revolution to a large dog?

Part the fur on the back of the dog’s neck, between the shoulder blades, and apply the full contents of the pipette directly to the skin. Avoid bathing or shampooing for at least 2 hours to ensure absorption.

Is Revolution safe for dogs under 8 weeks old?

No, Revolution is not recommended for puppies younger than 8 weeks. It’s approved for dogs 8 weeks and older weighing between 40.1 and 85 pounds. Always consult your vet before starting any new treatment.

Can Revolution be used year-round?

Yes, Revolution is designed for year-round monthly use. Continuous application ensures uninterrupted protection against heartworm, fleas, ticks, and mites, especially important in climates with extended parasite seasons.

How much does Revolution Large Dogs 40.1-85lbs (Green) 12 Doses cost?

Revolution Large Dogs 40.1-85lbs (Green) 12 Doses is $227.59 at BestVetCare. Prices may change — click through to BestVetCare for the latest.

Is Revolution Large Dogs 40.1-85lbs (Green) 12 Doses in stock at BestVetCare?

Yes, Revolution Large Dogs 40.1-85lbs (Green) 12 Doses is currently in stock at BestVetCare.

Are there coupon codes for BestVetCare?

Yes — Love Those Deals currently tracks 4 active BestVetCare coupons. See the coupons section on this page to copy a code before checkout.

Specifications

Brand
Revolution
Product Type
Animals & Pet Supplies > Pet Supplies > Dog Supplies
Category
Animals & Pet Supplies > Pet Supplies > Dog Supplies
SKU
3913
MPN
Zoetis-Revolution-104
Last updated Apr 28, 2026